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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
121 Results for "
ACAT
" in MedChemExpress (MCE) Product Catalog:
Products (121)
121 Results for "ACAT" in MCE Product Catalog:
Cat. No.: HY-P78986A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACAT1; Acetyl-Coenzyme A Acetyltransferase 1; Prev. ACAT; MAT; Acetyl-CoA Acetyltransferase, Mitochondrial; T2; Acetoacetyl-CoA Thiolase; Mitochondrial Acetoacetyl-CoA Thiolase; THIL; Testicular Tissue Protein Li 198; Acetyl-CoA Acetyltransferase 1; Aceto
Species:
Human
Source:
E. coli
Cat. No.: HY-105445R
CAS No.: 135025-12-6
Target:
Research Areas:
CP-113818 (Standard) is the analytical standard of CP-113818 (HY-105445). This product is intended for research and analytical applications. CP-113818 is a potent cholesterol acyltransferase (ACAT) inhibitor. CP-113818 can be used for the research of Alzheimer's disease .
Cat. No.: HY-P82226A
Synonyms: T2; MAT; ACAT; THIL
Cat. No.: HY-138198
CAS No.: 214265-97-1
Target:
Research Areas:
(E)-YIC-C8-434 is the E double-bond configuration of YIC-C8-434. YIC-C8-434 is an orally active ACAT inhibitor with anti-hypercholesterolemic activity .
Cat. No.: HY-P7730
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine Carboxylesterase; Carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; HCE-1; Carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; Human Monocyte/Macrophage Serine
Species:
Human
Source:
HEK293
Cat. No.: HY-P11865
CAS No.: 2379342-67-1
Cat. No.: HY-101576R
CAS No.: 136609-26-2
Target:
Research Areas:
RP 70676 (Standard) is the analytical standard of RP 70676 (HY-101576). This product is intended for research and analytical applications. RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT.
Cat. No.: HY-138198A
Target:
Research Areas:
YIC-C8-434 is an orally active ACAT inhibitor. YIC-C8-434 selectively blocks cholesterol esterification in intestinal epithelial cells and hepatocytes without affecting the production of triglycerides or phospholipids. YIC-C8-434 effectively reduces intracellular cholesteryl ester levels and induces an increase in lipid droplet volume, exhibiting excellent cholesterol-lowering activity and safety. YIC-C8-434 disrupts the assembly of hepatitis C virus (HCV) virions, reduces HCV RNA synthesis and viral particle release. YIC-C8-434 can be used in studies related to hepatitis C virus infection .
Cat. No.: HY-N17326
CAS No.: 242794-72-5
Cat. No.: HY-N18066
CAS No.: 854381-37-6
Category:
Cat. No.: HY-107396R
CAS No.: 138046-43-2
Target:
Research Areas:
YM-750 (Standard) is the analytical standard of YM-750 (HY-107396). This product is intended for research and analytical applications. YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .
Cat. No.: HY-P88953A
Synonyms: ACACT2; ACAT2; ARGP2
Cat. No.: HY-19140
CAS No.: 124884-99-7
Target:
Research Areas:
YM17E hydrochloride is an acyl CoA:cholesterol acyltransferase (ACAT) inhibitor, with IC50 of 44 nM. YM17E hydrochloride has hypocholesterolemic effect .
Cat. No.: HY-100401AR
CAS No.: 608510-47-0
Synonyms: CS-505 (Standard)
Target:
Research Areas:
Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively . Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity .
Cat. No.: HY-167717
CAS No.: 191791-65-8
Synonyms: (Rac)-F 12511
Target:
Research Areas:
(Rac)-Eflucimibe ((Rac)-F 12511) is an ACAT inhibitor with endogenous hypercholesterolemia modulating activity. (Rac)-Eflucimibe has shown high potency and efficacy as an anti-hypercholesterol compound in different hypercholesterolemia animal models .
Cat. No.: HY-P75543
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACAT2; Acetoacetyl Coenzyme A Thiolase; Acetyl-CoA Acetyltransferase 2; Acetyl-Coenzyme A Acetyltransferase 2 (Acetoacetyl Coenzyme A Thiolase); Acetyl-CoA Acetyltransferase, Cytosolic; Acetyl-Coenzyme A Acetyltransferase 2; Acetyl-CoA Transferase-Like Pr
Species:
Rat
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
