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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
105 Results for "
dimeric
" in MedChemExpress (MCE) Product Catalog:
Products (105)
105 Results for "dimeric" in MCE Product Catalog:
Cat. No.: HY-NP065E
Synonyms: DSL-AF594
Cat. No.: HY-NP065H
Synonyms: DSL-AF647
Cat. No.: HY-NP065I
Synonyms: DSL-AF680
Cat. No.: HY-NP065J
Synonyms: DSL-Cy3
Cat. No.: HY-NP065K
Synonyms: DSL-Cy5
Cat. No.: HY-NP065L
Synonyms: DSL-Cy7
Cat. No.: HY-185668
CAS No.: 162554-02-1
Target:
Research Areas:
2',5'-Dideoxy-3'-ATP is an adenylate cyclase inhibitor. 2',5'-Dideoxy-3'-ATP exerts linear noncompetitive inhibition via binding to the distinct P-site. 2',5'-Dideoxy-3'-ATP binds and stabilizes the dimeric form of Mycobacterium avium adenylyl cyclase Ma1120 to inhibit activity .
Cat. No.: HY-P11773
CAS No.: 1094848-94-8
Research Areas:
Cat. No.: HY-P11882
CAS No.: 947545-69-9
Target:
Research Areas:
Target:
Cat. No.: HY-P11786
CAS No.: 1020264-43-0
Target:
Research Areas:
SYN1327 is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 can be used in studies related to IgG-mediated autoimmune diseases .
Cat. No.: HY-P11786A
Target:
Research Areas:
SYN1327 acetate is a potent monomeric cyclic competitive antagonistic peptide targeting the neonatal Fc receptor (FcRn), with a Kd of 31 nM for human FcRn at pH 6 and a Kd of 170 nM at pH 7.4. SYN1327 acetate competitively binds to the IgG-binding site of FcRn and inhibits the binding of human IgG to FcRn. SYN1327 acetate acts as the monomeric precursor of the dimeric peptide SYN1436 (HY-P11882). SYN1327 acetate can be used in studies related to IgG-mediated autoimmune diseases .
Cat. No.: HY-P7477
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ALDH3A1; Aldehyde Dehydrogenase 3 Family, Member A1; Prev. ALDH3; Aldehyde Dehydrogenase Type III; Aldehyde Dehydrogenase, dimeric NADP-Preferring; Stomach Aldehyde Dehydrogenase; Aldehyde Dehydrogenase Family 3 Member A1; Aldehyde Dehydrogenase 3; ALDHII
Species:
Human
Source:
HEK293
Cat. No.: HY-P75568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ALDH3A1; Aldehyde Dehydrogenase 3 Family, Member A1; Prev. ALDH3; Aldehyde Dehydrogenase Type III; Aldehyde Dehydrogenase, dimeric NADP-Preferring; Stomach Aldehyde Dehydrogenase; Aldehyde Dehydrogenase Family 3 Member A1; Aldehyde Dehydrogenase 3; ALDHII
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181850
CAS No.: 3094716-52-3
Research Areas:
Telomeric G4s ligand 2 is an orally active, selective ligand of telomeric G-quadruplex (G4), with an IC50 of 0.4 μM. Telomeric G4s ligand 2 binds to dimeric telomeric G4, inhibits the activities of DHX36 and BLM helicases. Telomeric G4s ligand 2 activates cGAS-STING and TERRA-ZBP1 pathways, inducing autophagy and G2/M cell cycle arrest, and exhibits antiproliferative effects across cancer cell lines. Telomeric G4s ligand 2 can be used for the study of colorectal cancer .
Cat. No.: HY-185217
CAS No.: 2429876-60-6
PPI stabilizer-1-1 (Compound 2) is a KRAS dimerizing agent. PPI stabilizer-1-1 dimerizes KRAS with a KD of 3.8 µM. PPI stabilizer-1-1 co-crystallizes with GCP-KRAS G12D. PPI stabilizer-1 can be used for the research of KRAS-driven cancers .
Cat. No.: HY-180787
G6374 is a IRE1 PRORAC degrader with DC50 values of 0.04 μM (AMO1) and 0.13 μM (KMS27), an EC50 value of 0.11 μM, and KD values of 0.56 nM and 90.2 nM for IRE1 and VHL, respectively. G6374 binds to the ATP pocket of the IRE1 kinase domain and VHL to form a ternary complex that recruits CRL2 VHL, inducing K48-linked polyubiquitination of IRE1 at lysine residues K704 and K717, which in turn drives proteasomal degradation of monomeric and dimeric IRE1. G6374 can be used for the research of multiple myeloma .
Cat. No.: HY-182006
CAS No.: 3118012-34-0
Target:
Research Areas:
TNF-α-IN-28 (compound 4ea) is a TNF-α and NF-κB inhibitor with anti-inflammatory activity. TNF-α-IN-28 inhibits TNF-α and NF-κB expression. TNF-α-IN-28 interacts with TNF-α dimer .
Cat. No.: HY-P11471
Research Areas:
Cat. No.: HY-P6300
CAS No.: 169062-92-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
