6903-12-4
Chemical Structure
Anabsinthin
- CAS No.: 6903-12-4
- Formula:C30H40O6
- Molecular Weight:496.64
InChIKey: XDKZYFZYOVAAKJ-MBUKJKCRSA-N
SMILES: C[C@@]12[C@]34C([C@@](O2)(CC[C@]5([H])[C@]4([H])OC([C@H]5C)=O)C)([H])[C@@](C1)([H])[C@@]6([H])[C@]3([H])C(C)=C7[C@]6([H])[C@@](O)(CC[C@]8([H])[C@]7([H])OC([C@H]8C)=O)C
Biological Activity: Anabsinthin is a dimeric sesquiterpene lactone. Anabsinthin can be found in Artemisia absinthium L. (wormwood). Anabsinthin modulates intracellular calcium levels, mediates anti-inflammatory and antioxidant effects. Anabsinthin inhibits Phorbol 12-myristate 13-acetate (HY-18739)-induced superoxide anion production, increased iNOS and MUC5AC protein expression, and IL-1β transcription upregulation. Anabsinthin can be used for the research of citrus canker[1][2][3].
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Anabsinthin | Anabsinthin is a dimeric sesquiterpene lactone. Anabsinthin can be found in Artemisia absinthium L. (wormwood). Anabsinthin modulates intracellular calcium levels, mediates anti-inflammatory and antioxidant effects. Anabsinthin inhibits Phorbol 12-myristate 13-acetate (HY-18739)-induced superoxide anion production, increased iNOS and MUC5AC protein expression, and IL-1β transcription upregulation. Anabsinthin can be used for the research of citrus canker. | |||||||||||||||||||||
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References
- [1]. Talmon M, et al. Anti-inflammatory Activity of Absinthin and Derivatives in Human Bronchoepithelial Cells. J Nat Prod. 2020 Jun 4;83 (6):1740-1750. [Content Brief]
- [2]. Aberham A, et al. Analysis of sesquiterpene lactones, lignans, and flavonoids in wormwood (Artemisia absinthium L.) using high-performance liquid chromatography (HPLC)-mass spectrometry, reversed phase HPLC, and HPLC-solid phase extraction-nuclear magnetic resonance. J Agric Food Chem. 2010;58(20):10817-10823. [Content Brief]
- [3]. Alam SA. Epicatechin gallate and anabsinthin: effective inhibitors of Xanthomonas citri for citrus canker control. Discover Chemistry. 2025 Apr 11;2:76.
