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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
88 Results for "
reflux
" in MedChemExpress (MCE) Product Catalog:
Products (88)
88 Results for "reflux" in MCE Product Catalog:
Cat. No.: HY-109023A
CAS No.: 955095-50-8
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Azeloprazole potassium is an orally active proton pump inhibitor. Azeloprazole potassium irreversibly binds to and blocks the proton pump (H +/K +-ATPase) on parietal cells, thereby inhibiting gastric acid secretion. Azeloprazole potassium is primarily metabolized by the CYP3A4 enzyme, and its pharmacokinetics and acid-suppressive effects are independent of CYP2C19 activity. Azeloprazole potassium can be used for research on acid-related diseases such as reflux esophagitis and gastroesophageal reflux disease .
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Metoclopramide dihydrochloride hydrate is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. Metoclopramide dihydrochloride hydrate can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis .
Cat. No.: HY-N9808
CAS No.: 1038602-12-8
Target:
Cat. No.: HY-B0732AS1
Synonyms: HSR803-d4 free base
Cat. No.: HY-N17783A
CAS No.: 163860-24-0
Category:
Ketones, Aldehydes, Acids Oyama sieboldii (K. Koch) N. H. Xia & C. Y. Wu Plants Magnoliaceae Extract
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Cat. No.: HY-111313R
CAS No.: 844645-08-5
Research Areas:
JNJ-26070109 (Standard) is the analytical standard of JNJ-26070109 (HY-111313). This product is intended for research and analytical applications. JNJ-26070109 is a high-affinity, competitive, orally bioactive, and selective cholecystoKinin 2 (CCK2) receptor antagonist with good pharmacoKinetic properties, with pKis of 8.49, 7.99, and 7.70 for human, rat, and dog CCK2 receptors, respectively. The dual function of CCK2 receptors in regulating gastric acid secretion and growth of the gastrointestinal mucosa make this an attractive and novel target for the research of gastroesophageal reflux disease .
Cat. No.: HY-182513
CAS No.: 459842-29-6
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Research Areas:
ONO-8539 is an orally active prostanoid EP1 receptor antagonist with competitive, insurmountable binding and slow receptor dissociation for long-duration inhibition. ONO-8539 modulates afferent nerve function related to bladder activity, inhibits detrusor overactivity-related contractions, decreases nonvoiding contractions and voiding duration, and increases uroflow rate with ATP (HY-B2176)-induced detrusor overactivity. ONO-8539 attenuates acid-induced heartburn symptoms, extends time to first heartburn sensation, and prevents primary hypersensitivity after distal esophageal acidification. ONO-8539 can be used for the research of overactive bladder and gastroesophageal reflux disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
