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Cat. No.: HY-111313R

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JNJ-26070109 (Standard)

JNJ-26070109 (Standard) is the analytical standard of JNJ-26070109 (HY-111313). This product is intended for research and analytical applications. JNJ-26070109 is a high-affinity, competitive, orally bioactive, and selective cholecystoK_inin 2 (CCK2) receptor antagonist with good pharmacoK_inetic properties, with pK_is of 8.49, 7.99, and 7.70 for human, rat, and dog CCK2 receptors, respectively. The dual function of CCK2 receptors in regulating gastric acid secretion and growth of the gastrointestinal mucosa make this an attractive and novel target for the research of gastroesophageal reflux disease.

For research use only. We do not sell to patients.

CAS No.: 844645-08-5
Formula: C₂₃H₁₇BrF₂N₄O₃S
Molecular Weight:547.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

JNJ-26070109 (Standard) Chemical Structure

CAS No.: 844645-08-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 844645-08-5
Molecular Weight 547.37
Formula C₂₃H₁₇BrF₂N₄O₃S
SMILES

O=C(N[C@@H](C1=CC=C(F)C=C1F)C)C2=CC=C(Br)C=C2NS(=O)(C3=C4N=CC=NC4=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Magda F Morton, et al. JNJ-26070109 [(R)4-bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide]: a novel, potent, and selective cholecystokinin 2 receptor antagonist with good oral bioavailability. J Pharmacol Exp Ther. 2011 J [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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