Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
140 Results for "
renal function
" in MedChemExpress (MCE) Product Catalog:
Products (140)
140 Results for "renal function" in MCE Product Catalog:
Cat. No.: HY-176238
Target:
Research Areas:
CX116 is an orally active anti-inflammatory agent. CX116 exerts its effects by inhibiting the inflammatory response, reducing oxidative stress, protecting mitochondrial function, and counteracting apoptosis. CX116 bears acceptable toxicity, and can significantly protect renal tissue from Cisplatin (HY-17394)-induced damage. CX116 can be used for the study of Cisplatin-induced acute kidney injury (cis-AKI) .
Category:
Target:
Research Areas:
Pramocaine (Pramoxine) is a topical surface anesthetic and antipruritic agent. Pramocaine reversibly inhibits voltage-gated sodium channel, reduces transmembrane permeability of sodium ions, stabilizes cell membranes, prevents depolarization, blocks action potential conduction, and inhibits peripheral slow C-fiber pathways associated with pain, pruritus and thermoception. Pramocaine can be used in research related to chronic pruritus, renal pruritus, atopic dermatitis, xerotic pruritus, uremic pruritus, and cutaneous hyperalgesia/pain .
Target:
Research Areas:
Pramocaine (Pramoxine) hydrochloride (Standard) is the analytical standard of Pramocaine hydrochloride (HY-B1319). This product is intended for research and analytical applications. Pramocaine hydrochloride is a topical surface anesthetic and antipruritic agent. Pramocaine hydrochloride reversibly inhibits voltage-gated sodium channel, reduces transmembrane permeability of sodium ions, stabilizes cell membranes, prevents depolarization, blocks action potential conduction, and inhibits peripheral slow C-fiber pathways associated with pain, pruritus and thermoception. Pramocaine hydrochloride can be used in research related to chronic pruritus, renal pruritus, atopic dermatitis, xerotic pruritus, uremic pruritus, and cutaneous hyperalgesia/pain .
Cat. No.: HY-B1319S1
Synonyms: Pramoxine-d9 hydrochloride
Cat. No.: HY-B1204S4
Synonyms: Ergamine-15N3
Cat. No.: HY-W424876
CAS No.: 6034-68-0
Target:
Research Areas:
N-(7H-Purin-6-yl)acetamide (Compound 25) is a selective adenosine receptor (AdeR) agonist with a Ki value of 0.515 μM for the human adenosine receptor and a Ki value of 2.85 μM for the rat adenosine receptor. N-(7H-Purin-6-yl)acetamide is promising for research of adenosine receptor function, pain perception, inflammatory responses, and renal function .
Cat. No.: HY-182000
CAS No.: 3055112-52-9
Research Areas:
Xanthine oxidase-IN-23 (Compound BPF) is an orally active, reversible, mixed-type Xanthine oxidase inhibitor with an IC50 of 3.33 μM. Xanthine oxidase-IN-23 directly binds to XOD in a reversible mixed-type manner to inhibit its catalytic activity. Xanthine oxidase-IN-23 upregulates ABCG2 and downregulates GLUT9 to promote renal urate excretion. Xanthine oxidase-IN-23 reduces serum urate levels and improves renal function in hyperuricemic mice. Xanthine oxidase-IN-23 can be used in the research of hyperuricemia .
Cat. No.: HY-P12125
Target:
Research Areas:
Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)
Target:
Research Areas:
Cat. No.: HY-P11210
CAS No.: 132309-52-5
Target:
Research Areas:
Cat. No.: HY-W588276
CAS No.: 180509-18-6
Target:
Research Areas:
2-α-D-Mannopyranosyl-L-tryptophan, a naturally occurring C-glycosylamino acid, is a novel biomarker of renal function.
Cat. No.: HY-187429
Research Areas:
Anti-aging agent 2 is an anti-aging agent. Anti-aging agent 2 attenuates senescence-associated secretory phenotype (SASP), alleviates cell cycle arrest, reduces the levels of senescence markers in renal tissues, and downregulates the expression of p21, p16 and p53 in the kidney. Anti-aging agent 2 improves renal function and alleviates renal fibrosis. Anti-aging agent 2 extends the lifespan of Caenorhabditis elegans. Anti-aging agent 2 can be used in the research of chronic kidney disease .
Cat. No.: HY-111282
CAS No.: 85394-14-5
Target:
Research Areas:
MK-789 is a competitive reversible inhibitor of dehydropeptidase I (DHP-I). MK-789 competitively blocks the entry of N-formimidoylthienamycin into proximal tubular cells, thereby inhibiting its renal metabolism. MK-789 shifts the renal excretion pathway of N-formimidoylthienamycin to glomerular filtration only, increasing its urinary recovery rate and renal clearance. MK-789 is applicable to studies on renal metabolism and pharmacokinetics .
Cat. No.: HY-N10625A
CAS No.: 2952-70-7
Synonyms: 5α-Cyprinol
Target:
Cat. No.: HY-N19615
CAS No.: 134859-90-8
Cat. No.: HY-183473
CAS No.: 34535-83-6
Target:
Research Areas:
Fenalcomine hydrochloride is an orally active phenethylamine derivative with antianginal activity. Fenalcomine hydrochloride reduces myocardial oxygen consumption, and increases cardiac output and coronary blood flow. Fenalcomine hydrochloride is suitable for angina models complicated by hypertension, diabetes, and old myocardial infarction. Fenalcomine hydrochloride can be used in studies related to angina pectoris .
Cat. No.: HY-183473A
CAS No.: 34616-39-2
Target:
Research Areas:
Fenalcomine is an orally active phenethylamine derivative with antianginal activity. Fenalcomine reduces myocardial oxygen consumption, and increases cardiac output and coronary blood flow. Fenalcomine is suitable for angina models complicated by hypertension, diabetes, and old myocardial infarction. Fenalcomine can be used in studies related to angina pectoris .
Cat. No.: HY-113281
CAS No.: 44843-89-2
Target:
fatty acids with medium chain lengths (particularly hexanoic acid). 5-Hydroxyhexanoic acid functions as a predictor of early renal functional decline in type 2 diabetes with microalbuminuria .
Cat. No.: HY-182714
CAS No.: 109292-91-3
Synonyms: N6-Cyclopentyl-9-methyladenine
Target:
Research Areas:
N 0840 is a neutral antagonist of adenosine A1 receptor (A1AR), with a Ki value of 279 nM in rats and 1185 nM in humans. N 0840 modulates adenosine A1 receptor to increase forskolin-induced cyclic 3′,5′-adenosine monophosphate production, with a GTP shift value close to 1. N 0840 can be used in studies of neuroprotection, cardiovascular/renal function[1].
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
