120 Results for "

sulfhydryl groups

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "sulfhydryl groups" in MCE Product Catalog:

Cat. No.: HY-174941
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
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Cat. No.: HY-100216R
CAS No.: 68181-17-9
Synonyms: SPDP Crosslinker (Standard); Py-ds-Prp-OSu (Standard)
Research Areas:  

Cancer

SPDP (Standard) is the analytical standard of SPDP (HY-100216). This product is intended for research and analytical applications. SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
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Cat. No.: HY-W1048555C
Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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Cat. No.: HY-W1048555E
Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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Cat. No.: HY-W1048555H
Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
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Cat. No.: HY-174953C
TPP-PEG5000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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Cat. No.: HY-174953D
TPP-PEG10000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
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Cat. No.: HY-D3291
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).
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Cat. No.: HY-N11739
CAS No.: 53658-84-7
Helenalin isobutyrate is an NF-κB (p65 subunit) inhibitor with anti-inflammatory activity. Helenalin isobutyrate irreversibly alkylates cysteine sulfhydryl groups in the p65 subunit to inhibit NF-κB complex DNA binding activity .
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Cat. No.: HY-141540S1
Lactyl-CoA-d3 is the deuterium labeled Lactyl-CoA (HY-141540). Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers.
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Cat. No.: HY-115891
CAS No.: 2279-64-3
Target:  

Bacterial Fungal

Research Areas:  

Infection

Phenylmercuriurea is an organomercurial fungicide. Phenylmercuriurea exerts antifungal and antibacterial effects by inhibiting the activity of key enzymes via the binding of mercury ions to sulfhydryl groups of microbial proteins. Phenylmercuriurea can be used in studies related to infections caused by phytopathogenic fungi and bacteria .
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Cat. No.: HY-D2763
CAS No.: 890928-51-5
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
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Cat. No.: HY-174961A
Synonyms: Fmoc-NH-PEG2000-Mal
Fmoc-PEG2000-Maleimide (Fmoc-NH-PEG2000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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Cat. No.: HY-174961B
Synonyms: Fmoc-NH-PEG3400-Mal
Fmoc-PEG3400-Maleimide (Fmoc-NH-PEG3400-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
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Cat. No.: HY-167036B
CAS No.: 3101670-33-8
Research Areas:  

Others

DMG-PEG3400-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG3400-Mal can be used for drug delivery .
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Cat. No.: HY-167036D
CAS No.: 3101670-33-8
Research Areas:  

Others

DMG-PEG10000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG10000-Mal can be used for drug delivery .
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Cat. No.: HY-D2530
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
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Cat. No.: HY-105789
CAS No.: 538-03-4
Target:  

HIV Bacterial

Research Areas:  

Infection Inflammation/Immunology

Oxophenarsine hydrochloride is an anti-syphilitic agent, and also has non-classical applications including treating chronic discoid lupus erythematosus, inhibiting HIV-1 protein synthesis, and prolonging the duration of insulin action . Oxophenarsine hydrochloride forms an unstable insulin complex via sulfhydryl groups or free amino groups, thereby prolonging the hypoglycemic effect of insulin. Oxophenarsine hydrochloride inhibits HIV-1-specific protein synthesis and virus production .
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Cat. No.: HY-D2883C
Synonyms: Rhodamine B-PEG2000-SH
RB-PEG2000-SH (Rhodamine B-PEG2000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
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Cat. No.: HY-D2512
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
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