1024 Results for "

H3

" in MedChemExpress (MCE) Product Catalog:
Products (1024)

1024 Results for "H3" in MCE Product Catalog:

Cat. No.: HY-P76062
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SETD7; KIAA1717; SET Domain Containing 7, Histone Lysine Methyltransferase; Set9; SET7/9; SET Domain Containing Lysine Methyltransferase 7; SET7; Lysine N-Methyltransferase 7; KMT7; H3-K4-HMTase SETD7; Histone-Lysine N-Methyltransferase SETD7; SET Domain
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P702951
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KDM4C; Jumonji Domain-Containing Protein 2C; Prev. JMJD2C; Lysine-Specific Demethylase 4C; GASC1; Tudor Domain Containing 14C; KIAA0780; JHDM3C; TDRD14C; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase; JmjC Domain-Containing Histone Demethylation Protein
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P76080
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SMYD3; SET And MYND Domain-Containing Protein 3; Prev. ZNFN3A1; Zinc Finger Protein, Subfamily 3A (MYND Domain Containing), 1; Prev. ZMYND1; [Histone H3]-Lysine(4) N-Trimethyltransferase; KMT3E; Alternative Protein SMYD3; Zinc Finger MYND Domain-Containin
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P700258
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SMYD3; SET And MYND Domain-Containing Protein 3; Prev. ZNFN3A1; Zinc Finger Protein, Subfamily 3A (MYND Domain Containing), 1; Prev. ZMYND1; [Histone H3]-Lysine(4) N-Trimethyltransferase; KMT3E; Alternative Protein SMYD3; Zinc Finger MYND Domain-Containin
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701404
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NR1H3; Liver X Receptor Alpha; Nuclear Receptor Subfamily 1 Group H Member 3; CDNA FLJ56172, Highly Similar To Oxysterols Receptor LXR-Alpha; LXR-A; Nuclear Receptor Subfamily 1, Group H, Member 3; RLD-1; Liver X Nuclear Receptor Alpha Variant 1; LXRa; Li
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701616
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PHF8; Lysine Demethylase 7B; PHD Finger Protein 8; KIAA1111; Histone Lysine Demethylase PHF8; JHDM1F; ZNF422; Jumonji C Domain-Containing Histone Demethylase 1F; KDM7B; Zinc Finger Protein 422; [Histone H3]-Dimethyl-L-Lysine(36) Demethylase PHF8; MRXSSD;
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701617
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PHF8; Lysine Demethylase 7B; PHD Finger Protein 8; KIAA1111; Histone Lysine Demethylase PHF8; JHDM1F; ZNF422; Jumonji C Domain-Containing Histone Demethylase 1F; KDM7B; Zinc Finger Protein 422; [Histone H3]-Dimethyl-L-Lysine(36) Demethylase PHF8; MRXSSD;
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701618
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM4A; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase 4A; Prev. JMJD2A; Lysine (K)-Specific Demethylase 4A; Prev. JMJD2; Lysine-Specific Demethylase 4A; JHDM3A; Jumonji Domain Containing 2A; KIAA0677; Tudor Domain Containing 14A; TDRD14A; Jumonji Domain C
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701619
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: KDM4A; [Histone H3]-Trimethyl-L-Lysine(9) Demethylase 4A; Prev. JMJD2A; Lysine (K)-Specific Demethylase 4A; Prev. JMJD2; Lysine-Specific Demethylase 4A; JHDM3A; Jumonji Domain Containing 2A; KIAA0677; Tudor Domain Containing 14A; TDRD14A; Jumonji Domain C
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P702887
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KMT2C; Homologous To ALR Protein; Prev. MLL3; Myeloid/Lymphoid Or Mixed-Lineage Leukemia 3; Histone-Lysine N-Methyltransferase 2C; [Histone H3]-Lysine(4) N-Methyltransferase; HALR; Histone-Lysine N-Methyltransferase MLL3; KIAA1506; Lysine N-Methyltransfer
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P703071
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SETDB1; ERG-Associated Protein With SET Domain; SET Domain Bifurcated Histone Lysine Methyltransferase 1; Histone H3-K9 Methyltransferase 4; SET Domain Bifurcated 1; Lysine N-Methyltransferase 1E; KMT1E; Tudor Domain Containing 21; ESET; Histone-Lysine N-
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P703604
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SETDB1; ERG-Associated Protein With SET Domain; SET Domain Bifurcated Histone Lysine Methyltransferase 1; Histone H3-K9 Methyltransferase 4; SET Domain Bifurcated 1; Lysine N-Methyltransferase 1E; KMT1E; Tudor Domain Containing 21; ESET; Histone-Lysine N-
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P705547
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SETD7; KIAA1717; SET Domain Containing 7, Histone Lysine Methyltransferase; Set9; SET7/9; SET Domain Containing Lysine Methyltransferase 7; SET7; Lysine N-Methyltransferase 7; KMT7; H3-K4-HMTase SETD7; Histone-Lysine N-Methyltransferase SETD7; SET Domain
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-159098
dWIZ-1 is an orally active molecular glue and chemical probe targeting the WIZ transcription factor, which based on an IMiD backbone, binding to human WIZ with an affinity of 3.5 μM. dWIZ-1 recruits WIZ to the cereblon-DDB1 complex via its ZF7 domain, thereby triggering proteasome-dependent degradation of WIZ. dWIZ-1 significantly induces fetal hemoglobin expression in erythroblasts while reducing the level of inhibitory H3K9 dimethylation at WIZ binding sites such as the β-globin locus. Meanwhile, dWIZ-1 does not affect the proliferation and differentiation of erythroblasts, and no cytotoxicity is observed in in vitro cells or cynomolgus monkey models. dWIZ-1 serves as a critical tool molecule for investigating the mechanism and underlying pathways of sickle cell disease .
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Cat. No.: HY-P991097
Synonyms: PM-8002; BNT-327

Target:  

VEGFR PD-1/PD-L1

Research Areas:  

Cancer

Pumitamig (PM-8002, BNT-327) is a bispecific antibody targeting PD-L1 and VEGF-A, with immune activation and anti-angiogenic activities. By binding to PD-L1, Pumitamig restores the function of effector T cells, while neutralizing VEGF-A in the tumor microenvironment to reverse its inhibition on the infiltration and activation of immune cells and normalize tumor blood vessels. Pumitamig can also be combined with various ADCs targeting TROP2, B7H3, HER2, HER3 for the research of advanced/metastatic solid tumors, including non-small cell lung cancer, ovarian cancer, triple-negative breast cancer, cervical cancer, etc. Pumitamig also exhibits potential efficacy in "cold" tumors with low PD-L1 expression that are insensitive to immunotherapy .
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Cat. No.: HY-P992482
VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease [3].
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Cat. No.: HY-P80905
Synonyms: SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P701405
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR1H3; Liver X Receptor Alpha; Nuclear Receptor Subfamily 1 Group H Member 3; CDNA FLJ56172, Highly Similar To Oxysterols Receptor LXR-Alpha; LXR-A; Nuclear Receptor Subfamily 1, Group H, Member 3; RLD-1; Liver X Nuclear Receptor Alpha Variant 1; LXRa; Li
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P702875
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KDM5A; Histone Demethylase JARID1A; Prev. RBBP2; RBP2; Prev. JARID1A; Jumonji, AT Rich Interactive Domain 1A (RBBP2-Like); Lysine-Specific Demethylase 5A; Jumonji, AT Rich Interactive Domain 1A (RBP2-Like); [Histone H3]-Trimethyl-L-Lysine(4) Demethylase 5
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P703046
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: KDM1B; BA204B7.3; Prev. AOF1; FLJ33898; Prev. C6orf193; FLJ43328; LSD2; [Histone-H3]-N(6),N(6)-Dimethyl-L-Lysine(4) FAD-Dependent Demethylase; Flavin-Containing Amine Oxidase Domain-Containing Protein 1; Amine Oxidase (Flavin Containing) Domain 1; Lysine-
Species:  
Mouse
Source:  
Sf9 insect cells
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