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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1088 Results for "
Staphylococcus
" in MedChemExpress (MCE) Product Catalog:
Products (1088)
1088 Results for "Staphylococcus" in MCE Product Catalog:
Cat. No.: HY-108988
CAS No.: 1622253-00-2
Research Areas:
Albicidin is a peptide antibiotic with phytotoxic activity. Albicidin potently inhibits bacterial and plant DNA gyrase at nanomolar concentrations, blocks DNA replication, and exhibits excellent antibacterial efficacy against multidrug-resistant bacteria. Albicidin possesses bactericidal activity against Gram-positive and Gram-negative microorganisms, and acts as a virulence factor for the systemic plant infection by Xanthomonas albilineans. Albicidin can be used in studies related to bacterial infections and sugarcane leaf blight .
Cat. No.: HY-129724A
CAS No.: 2828433-34-5
Synonyms: ACTH-(11-13) acetate; Lys-Pro-Val acetate; H-Lys-Pro-Val-OH acetate
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Target:
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Mal-Deferoxamine is a maleimide-functionalized trihydroxamate siderophore derivative that can be isolated from Streptomyces pilosus. Mal-Deferoxamine possesses highly specific Fe (III) chelating ability, and the stability of complexes formed between it and non-Fe (III) metal ions is significantly lower. Mal-Deferoxamine exhibits growth inhibitory effects against Gram-positive bacteria, but shows no obvious inhibitory activity against Gram-negative bacteria (MIC>50 μM). Mal-Deferoxamine is mainly suitable for scientific research in hematology and related fields .
Cat. No.: HY-183712
Research Areas:
Antibacterial agent 345 is a Ciprofloxacin (HY-B0356)-lipophilic derivative and is an antibacterial agent. Antibacterial agent 345 inhibits DNA gyrase and inhibits bacterial DNA replication and transcription. Antibacterial agent 345 inhibits bacterial biofilm formation. Antibacterial agent 345 can be used for the research of bacterial infections, such as Pseudomonas aeruginosa infection .
Cat. No.: HY-184587
Research Areas:
Antibacterial agent 356 is an orally active antibacterial agent. Antibacterial agent 356 binds to the Mrr1 transcription factor, inhibits the expression of the MDR1 efflux pump gene, reduces the efflux of Rhodamine 123, and increases the accumulation of intracellular substrates in drug-resistant Candida albicans cells. Antibacterial agent 356 induces mitochondrial membrane potential reduction and ROS accumulation in Candida albicans, inhibits the yeast-hypha transition process, and suppresses its biofilm formation. Antibacterial agent 356 reverses efflux pump-mediated drug resistance in azole-resistant Candida albicans with overexpressed Mdr1. Antibacterial agent 356 improves the survival rate of Galleria mellonella larvae infected with azole-resistant Candida albicans*CA632, and reduces the renal fungal load and renal tissue damage in infected BALB/c mice. Antibacterial agent 356 can be used for the research of Candida albicans infection .
Cat. No.: HY-N1341
CAS No.: 54835-70-0
Target:
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Roseoside is an inhibitor of DNA gyrase and HAV 3C protease, and also inhibits HCV NS5A/B replicase in human systems with an IC50 of 20 μM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase (IC50=20 μM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV .
Cat. No.: HY-N17436
CAS No.: 138870-92-5
Category:
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Cat. No.: HY-N21846
CAS No.: 82516-67-4
Category:
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Cat. No.: HY-P0307B
CAS No.: 393511-85-8
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Cat. No.: HY-P10159
CAS No.: 1809102-71-3
Target:
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DJK-5 is an antimicrobial peptide that targets and degrades guanosine pentaphosphate and tetraphosphate (pppGpp and ppGpp). DJK-5 kills bacteria within dentinal tubules, dental plaque and preformed oral biofilms, delays biofilm recovery, reduces the abundance of extracellular polysaccharides and the structural integrity of biofilm matrices, and inhibits the formation and biomass accumulation of dental plaque biofilms. DJK-5 permeabilizes bacterial membranes, induces bacterial morphological changes, inhibits bacterial growth, and exerts a synergistic effect on bacterial biofilms when used in combination with traditional antibiotics and Colistin (HY-113678). DJK-5 exhibits protease resistance and broad-spectrum antibiofilm activity, though its activity decreases in fetal bovine serum. DJK-5 can be used in studies of pulpitis, mixed biofilm infections, skin abscesses, dental caries, infections associated with failed root canal therapy, and Pseudomonas aeruginosa biofilm-related respiratory tract infections .
Cat. No.: HY-W353842
CAS No.: 32426-11-2
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Octyl decyldimethyl ammonium chloride, a quaternary ammonium salt, is an antibacterial agent. Octyl decyldimethyl ammonium chloride disrupts cell membranes, leading to cytotoxicity. Octyl decyldimethyl ammonium chloride has risk of skin irritation and increases pro-inflammatory IL-1α secretion .
Cat. No.: HY-N22017
CAS No.: 2341324-20-5
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Cat. No.: HY-P11242
Research Areas:
Cat. No.: HY-187932
CAS No.: 77360-52-2
Research Areas:
Ceftiolene is a cephalosporin that inhibits Gram-negative bacteria. Ceftiolene binds to PBP. Ceftiolene induces bacterial lysis, autolytic activity, filamentation, and porin regulation. Ceftiolene can be used in research on bacterial infections and Pseudomonas aeruginosa infections .
Cat. No.: HY-N10184
CAS No.: 540770-33-0
Synonyms: FKI-0550
Cat. No.: HY-N10343
CAS No.: 19237-18-4
Category:
Natural Products other families Other Diseases Glucosinolates Plants Disease Research Fields
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Cat. No.: HY-N19212
CAS No.: 3040055-59-9
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Cat. No.: HY-N20633
CAS No.: 1378990-15-8
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Cat. No.: HY-N20699
CAS No.: 3131756-59-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
