Paecilaminol
Paecilaminol is an amino alcohol and NADH-fumarate reductase inhibitor (IC50 = 5.1 μM against Ascaris suum) that also inhibits both helminth and mammalian mitochondrial complexes I and III, exhibiting antifungal, antibacterial, nematocidal, insecticidal, and cancer cell growth-inhibitory activities. Paecilaminol can be used in research on helminth infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 540770-33-0
- 分子式: C20H43NO
- 分子量:313.56
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
体外実験
Paecilaminol inhibits Ascaris suum NADH-fumarate reductase with an IC50 of 5.1 μM, and this inhibition is not affected by the presence of 30 mg/mL bovine serum albumin[5].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 540770-33-0
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分子量 313.56
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分子式 C20H43NO
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SMILES
CC(N)C(O)CCCCCCCCCCC(C)CC(C)CC
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別名
FKI-0550
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Structure Classification
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Initial Source
Paecilomyces sp.
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Chen W, et al. Secondary Metabolites of Purpureocilliumlilacinum. Molecules. 2021 Dec 21;27(1):18.
[3]. Ui H, et al. Paecilaminol, a new NADH-fumarate reductase inhibitor, produced by Paecilomyces sp. FKI-0550. J Antibiot (Tokyo). 2006 Sep;59(9):591-6. [Content Brief]
[5]. Ui H, et al. Paecilaminol, a new NADH-fumarate reductase inhibitor, produced by Paecilomyces sp. FKI-0550. The Journal of antibiotics. 2006 Sep;59(9):591-6. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Paecilaminol 関連分類
HY-N10184 関連分類
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