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Art. -Nr.: HY-N20699

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Geministatin C

Geministatin C is a depside analog derived from Geministatin A (HY-N20700) that exhibits mammalian cytotoxicity against cancer cells and fibroblasts. Geministatin C shows no significant antibacterial activity against Gram-positive bacteria and no antifungal activity against yeast.

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CAS. Nr.: 3131756-59-4
Formel: C₃₁H₄₈O₉
Molecular Weight:564.71

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Geministatin C Chemical Structure

CAS. Nr.: 3131756-59-4

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Geministatin C exhibits no significant antibacterial activity against Bacillus subtilis, Staphylococcus aureus, or methicillin-resistant S. aureus, with MIC values > 100 μg/mL for all three bacterial strains^[1].
Geministatin C exhibits no significant antifungal activity against Saccharomyces cerevisiae, with an MIC value > 200 μg/mL^[1].
Geministatin C exhibits cytotoxicity against mouse myeloma NS-1 cells with an IC₅₀ of 17 μM and against neonatal foreskin fibroblast (NFF) cells with an IC₅₀ of 19 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3131756-59-4
Molecular Weight 564.71
Formel C₃₁H₄₈O₉
SMILES

CCCCC/C=C\C/C=C\CCCCCCCC(C=C1O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O)=C(C(O)=C1)C(OC)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganisms
Austroacremonium gemini
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Crombie A, et al. Geministatins: new depside antibiotics from the fungus Austroacremonium gemini. The Journal of antibiotics. 2024 Oct;77(10):639-646. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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