54835-70-0
Chemical Structure
Roseoside
- CAS No.: 54835-70-0
- Formula:C19H30O8
- Molecular Weight:386.44
IUPAC Name: (S)-4-hydroxy-3,5,5-trimethyl-4-((R,E)-3-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-1-en-1-yl)cyclohex-2-en-1-one
InChIKey: SWYRVCGNMNAFEK-MHXFFUGFSA-N
SMILES: C[C@@H](O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]([C@H]1O)CO)/C=C/[C@](C(C)(C2)C)(C(C)=CC2=O)O
Biological Activity: Roseoside is an inhibitor of DNA gyrase and HAV 3C protease, and also inhibits HCV NS5A/B replicase in human systems with an IC50 of 20 μM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase (IC50=20 μM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Roseoside | 96.99% | Roseoside is an inhibitor of DNA gyrase and HAV 3C protease, and also inhibits HCV NS5A/B replicase in human systems with an IC50 of 20 μM. Roseoside binds to the active site of enzymes and stabilizes the interaction by forming hydrogen bonds with key amino acid residues. Roseoside inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans, and interferes with HCV RNA replication in vitro by inhibiting HCV NS5A/B replicase (IC50=20 μM). Roseoside shows no cytotoxicity and serves as a research tool for studies related to bacterial infections, candidiasis, HAV and HCV. | ||||||||||||||||||||
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- [1]. Mohamed M F S, et al. Bioactive potential of Latania verschaffeltii Lem. leaves (Arecaceae): phytochemical, antimicrobial, antiviral, and computational evaluation[J]. The Science of Nature, 2026, 113(2): 40.
- [2]. Lee J K, et al. Roseoside Is a Bioactive Compound in Kirengeshoma koreana Nakai Extract with Potent In Vitro Antiviral Activity Against Hepatitis C Virus[J]. Molecules, 2024, 29(21): 5130.
Keywords
