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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
673 Results for "
K-Ras
" in MedChemExpress (MCE) Product Catalog:
Products (673)
673 Results for "K-Ras" in MCE Product Catalog:
Cat. No.: HY-146476
CAS No.: 2230873-66-0
KRAS inhibitor-18 (compound 3-10) is a potent KRAS G12C inhibitor with an IC50 of 4.74 µM. KRAS inhibitor-18 shows p-ERK inhibition activities with IC50s of 66.4, 11.1 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-18 has the potential for the research of pancreatic, colorectal, and lung cancers .
Cat. No.: HY-146533
CAS No.: 2230874-00-5
KRAS inhibitor-12 (compound 6-1) is a potent KRAS G12C inhibitor with an IC50 of 0.537 µM. KRAS inhibitor-12 shows p-ERK inhibition activities with IC50s of 1.3, 3.7 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-12 has the potential for the research of pancreatic, colorectal, and lung cancers .
Cat. No.: HY-159473
CAS No.: 3024991-82-7
K-Ras-IN-3 (compound 3) is a potent GDP-KRAS G12V inhibitor with an IC50 value of 0.371 nM. K-Ras-IN-3 has the potential for the research of cancer .
Cat. No.: HY-187067
Research Areas:
K-Ras ligand-linker conjugate 9 is a conjugate of a target protein ligand and a linker, which can be used for the synthesis of PROTACs, such as PROTAC K-Ras Degrader-1 (HY-129523) .
Target:
Research Areas:
K-Ras-PDEδ-IN-1 is a novel and potent competitive K-Ras-PDEδ inhibitor. K-Ras-PDEδ-IN-1 binds to the farnesyl binding pocket of PDEδ with a low nanomolar Kd of 8 nM .
Cat. No.: HY-RS07426
Target:
Research Areas:
Kras Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kras gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07427
Target:
Research Areas:
Kras Rat Pre-designed siRNA Set A contains three designed siRNAs for Kras gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07425
Target:
Research Areas:
KRAS Human Pre-designed siRNA Set A contains three designed siRNAs for KRAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-159475
CAS No.: 3030577-05-7
KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM against KRas G12V, KRas WT and KRas G12R .
Cat. No.: HY-169312
CAS No.: 3059496-10-2
KRAS inhibitor-38 (Example 18) is a KRAS inhibitor that effectively suppresses the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo .
Cat. No.: HY-168442
CAS No.: 3059496-56-6
KRAS inhibitor-40 (Compound 41) is a KRAS inhibitor that interferes with the KRAS G12C-BRAF complex. KRAS inhibitor-40 inhibits the ERK phosphorylation of KRAS downstream signaling pathway. KRAS inhibitor-40 can inhibit the proliferation of tumor cells with different KRAS mutation types and has antitumor activity .
Cat. No.: HY-151287
CAS No.: 2411786-32-6
KRAS inhibitor-20 is a small molecular inhibitor of KRas G12C, the oncogenic mutant. KRAS inhibitor-20 inhibits KRas G12C with the IC50 value <10 nM .
Cat. No.: HY-164632
CAS No.: 3056974-05-8
KRAS inhibitor-32 (compound 139A) is a KRAS inhibitor. KRAS inhibitor-32 can be used in anti-cancer research .
Cat. No.: HY-162976
CAS No.: 3030078-96-4
KRAS inhibitor-35 (compound 72) is a KRAS inhibitor, with IC50 of 2 nM. KRAS inhibitor-35 can be used in tumor research .
Cat. No.: HY-162974
CAS No.: 3030078-43-1
KRAS inhibitor-34 (compound 27) is a KRAS inhibitor, with IC50 of 6.4 nM. KRAS inhibitor-34 can be used in tumor research .
Cat. No.: HY-145436
CAS No.: 2761218-40-8
KRAS inhibitor-11 (compound 12) is a KRAS inhibitor .
Cat. No.: HY-162983
CAS No.: 332373-49-6
KRAS inhibitor-36 (compund Abd2) directly inhibits KRAS Q61H .
Cat. No.: HY-160220S
CAS No.: 2641747-55-7
Cat. No.: HY-135866
CAS No.: 2022986-70-3
KRAS inhibitor-8 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound C .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
