KRAS inhibitor-40
KRAS inhibitor-40 (Compound 41) is a KRAS inhibitor that interferes with the KRAS G12C-BRAF complex. KRAS inhibitor-40 inhibits the ERK phosphorylation of KRAS downstream signaling pathway. KRAS inhibitor-40 can inhibit the proliferation of tumor cells with different KRAS mutation types and has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3059496-56-6
- Formula: C53H68ClF4N9O8S
- Molecular Weight:1102.67
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
KRas G12C |
Chemical Information
-
CAS No. 3059496-56-6
-
Molecular Weight 1102.67
-
Formula C53H68ClF4N9O8S
-
SMILES
O=C([C@H](F)Cl)N1CCC(C(N([C@H](C(N[C@H](C(N2N[C@H](C(OCC(C)(C)CC3=C(C4=C([C@H](C)OC)N=CC(N5CCOCC5)=C4)N6CC(F)(F)C7)=O)CCC2)=O)CC8=NC(C9=CC7C6C3=C9)=CS8)=O)C(C)C)C)=O)(F)CC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)