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KRAS inhibitor-12

KRAS inhibitor-12 (compound 6-1) is a potent KRAS G12C inhibitor with an IC50 of 0.537 µM. KRAS inhibitor-12 shows p-ERK inhibition activities with IC50s of 1.3, 3.7 µM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-12 has the potential for the research of pancreatic, colorectal, and lung cancers.

For research use only. We do not sell to patients.

  • CAS No.: 2230874-00-5
  • Formula: C19H16Cl2FN5OS
  • Molecular Weight:452.33
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • KRAS inhibitor-12 Chemical Structure
    KRAS inhibitor-12 Chemical Structure
CAS No.: 2230874-00-5
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  • KRAS inhibitor-12 Chemical Structure
    KRAS inhibitor-12 Chemical Structure
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  • KRAS inhibitor-12