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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
175 Results for "
Cs
" in MedChemExpress (MCE) Product Catalog:
Products (175)
175 Results for "Cs" in MCE Product Catalog:
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Research Areas:
HG-14-10-04 is a potent ALK and mutant EGFR inhibitor with IC50s of 20 nM, 15.6 nM, 22.6 nM and 124.5 nM for ALK, EGFR LR/TM, EGFR 19del/TM/CS and EGFR LR/TM/CS, respectively. HG-14-10-04 can be used to research anticancer .
Cat. No.: HY-P990644
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Cat. No.: HY-169982
CAS No.: 3064450-12-7
EGFR-IN-136 (compound 21v) is a potent EGFR inhibitor with IC50 values of 20.2, 1.2, 2.3, 12.5 nM for EGFR WT, EGFR LR/TM, EGFR 19D/TM/CS, EGFR LR/TM/CS, respectively. EGFR-IN-136 shows antiproliferative activity. EGFR-IN-136 shows antitumor activity and has the potential for the research of NSCLC .
Cat. No.: HY-P81432A
Synonyms: 19A; Cs1; SLAMF7; SLAM family member 7
Cat. No.: HY-14955A
CAS No.: 347870-26-2
Synonyms: (Rac)-MB06322; (Rac)-Cs-917
(Rac)-Managlinat dialanetil ((Rac)-MB06322) is a compound for the inhibition of type 2 diabetes that is in Phase II clinical trials and works by inhibiting gluconeogenesis.
Cat. No.: HY-178019
CAS No.: 3044733-61-8
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NDM-1-IN-10 (Compound CS-23) is an irreversible and covalent New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 36 nM. NDM-1-IN-10 shows a synergistic effect with Meropenem (HY-13678) against NDM-1-expressing E. coli ( MIC of 0.25 μg/mL for E. coli BL21/pET15b-blaNDM-1). NDM-1-IN-10 can be used for bacterial infections research .
Cat. No.: HY-17005S
CAS No.: 1127298-67-2
Cat. No.: HY-171958
CAS No.: 2654821-05-1
PROTAC EGFR degrader 12 (example 1) is a PROTAC degrader targeting EGFR that can effectively degrade EGFR mutants, but has little effect on EGFR WT. PROTAC EGFR degrader 12 shows IC50s against EGFR L858R-T790M (NCI-H1975 cells), EGFR L858R (NCI-H3255 cells), and EGFR L858R-T790M-L797S (NCI-H1975+CS cells) of all <50 nM .
Cat. No.: HY-143445
CAS No.: 2882851-77-4
EGFR-IN-48 is a potent and orally active EGFR inhibitor with IC50s of 0.193 nM, 0.251 nM, 10.4 nM for EGFR d19/TM/CS, EGFR LR/TM/CS, EGFR WT, respectively. EGFR-IN-48 inhibits the proliferation of BaF3 EGFR del19/T790M/C797S and PC-9 EGFR del19/T790M/C797S cells with IC50s of 1.526, 66.7 nM, respectively .
Cat. No.: HY-184611
Selenium (Se) is an essential trace element for the human body, playing a vital role in various physiological activities. In the body, selenium is bound to selenocysteine, an amino acid used to synthesize several selenoproteins. Selenium is often the active site of these proteins, playing a crucial role in maintaining intracellular redox balance. Chitosan-stabilized selenium nanoparticles (CS-SeNPs) are nanomaterials using the biopolymer chitosan (CS) as a stabilizer. Through electrostatic interactions, chitosan coats the surface of selenium nanoparticles (Se NPs), improving their dispersibility, stability, and biocompatibility. Se NPs themselves are characterized by low toxicity and high bioactivity, and the introduction of chitosan further enhances their functionality and application potential, making them widely recognized in biomedicine, food, and agriculture.
Cat. No.: HY-P87043
Synonyms: Choriomammotropin antibody; Chorionic somatomammotropin A antibody; chorionic somatomammotropin B antibody; chorionic somatomammotropin hormone 1 (placental lactogen) antibody; Chorionic somatomammotropin hormone 1 antibody; chorionic somatomammotropin hormone 2 antibody; Chorionic somatomammotropin hormone antibody; Cs 2 antibody; Cs-2 antibody; Cs1 antibody; Choriomammotropin antibody; Chorionic somatomammotropin A antibody; chorionic somatomammotropin B antibody; chorionic somatomammotropin hormone 1 (placental lactogen) antibody; Chorionic somatomammotropin hormone 1 antibody; chorionic somatomammotropin hormone 2 antibody; Chorionic somatomammotropin hormone antibody; Cs 2 antibody; Cs-2 antibody; Cs1 antibody; CsA antibody; CsB antibody; CsH_HUMAN antibody; CsH1 antibody; CsH2 antibody; CsMT antibody; hCs B antibody; hCs-B antibody; hCsA antibody; Lactogen antibody; mPL II antibody; PL antibody; PL1 antibody; Placental lactogen antibody; Prl3b1 antibody; prolactin family 3, subfamily b, member 1 antibody;
Cat. No.: HY-W667933
CAS No.: 17795-24-3
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S-Propyl-L-cysteine sulfoxide is an S-alkyl-L-cysteine sulfoxide and also a specific marker compound in Allium plants. S-Propyl-L-cysteine sulfoxide serves as a precursor of volatile alkyl disulfides, which produce the characteristic odor of Allium plants under the action of CS-lyase .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
