1680 Results for "

precursor

" in MedChemExpress (MCE) Product Catalog:
Products (1680)

1680 Results for "precursor" in MCE Product Catalog:

製品番号: HY-P1838
CAS 番号: 166798-69-2
研究分野:  

Cardiovascular Disease

Proadrenomedullin (45-92), human is a peptide corresponding to amino acids 45-92 of human preproadrenomedullin. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products .
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製品番号: HY-P7126
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Human
Source:  
CHO
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製品番号: HY-P71215
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: PLXDC2; Plexin Domain-Containing Protein 2; Plexin Domain Containing 2; FLJ14623; TEM7R; Tumor Endothelial Marker 7-Related precursor; PLXDC2-OT; 1200007L24Rik; Tumor Endothelial Marker 7-Related Protein
Species:  
Mouse
Source:  
HEK293
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製品番号: HY-P700832
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: PLXDC2; Plexin Domain-Containing Protein 2; Plexin Domain Containing 2; FLJ14623; TEM7R; Tumor Endothelial Marker 7-Related precursor; PLXDC2-OT; 1200007L24Rik; Tumor Endothelial Marker 7-Related Protein
Species:  
Human
Source:  
HEK293
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製品番号: HY-P706140
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Genome polyprotein; Core protein precursor; Capsid protein C; p23; Envelope glycoprotein E1; gp32; gp35; Envelope glycoprotein E2; NS1; gp68; gp70; Viroporin p7; Mature core protein; p21
Species:  
Virus
Source:  
E. coli
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製品番号: HY-P706278
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: ¹⁵N-ProGRP; ¹⁵N-Pro-gastrin-releasing peptide; ¹⁵N-PreproGRP; ¹⁵N-GRP precursor; Neuromedin C; Prepro-GRP; Bombesin; Pre-Progastrin Releasing Peptide; Testicular Tissue Protein Li 103; ProGRP; GRP-10; BN
Species:  
Human
Source:  
E. coli
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製品番号: HY-113224R
CAS 番号: 313-04-2
Desmosterol (Standard) is the analytical standard of Desmosterol. This product is intended for research and analytical applications. Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].
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製品番号: HY-148285
CAS 番号: 604-98-8
別名: Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Succinyl CoA (Succinyl-coenzyme A) is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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製品番号: HY-178271
CAS 番号: 147597-66-8
Target:  

Drug Intermediate

研究分野:  

Cancer

P-SCN-Bn-NOTA is a metal chelator and molecular imaging probe precursor that allows radiolabeling with Ga-68. P-SCN-Bn-NOTA can be conjugated to CD70-specific molecules B3, B6, ABDB3 and ABDB6 to form NOTA-labeled derivatives. P-SCN-Bn-NOTA is applicable for preclinical PET/CT imaging of CD70-expressing tumors in NCG mouse PDX models. P-SCN-Bn-NOTA can be used in studies related to CD70-positive tumors .
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製品番号: HY-180306
CAS 番号: 84693-92-5
Fluoroestradiol is an Estrogen receptor PET imaging tracer precursor. Fluoroestradiol, when radiolabeled with 18F, can be used as an Estrogen receptor PET imaging tracer. 18F-Fluoroestradiol exhibits the highest uptake selectivity and target-to-background ratio among
several 18F-labeled estrogens. 18F-Fluoroestradiol has demonstrated Estrogen receptor expression in normal brain tissues and in meningiomas. 18F-Fluoroestradiol can quantify regional Estrogen receptor expression in breast cancer. 18F-Fluoroestradiol has potential applications in assessing and monitoring heterogeneity in ovarian cancer .
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製品番号: HY-189236
CAS 番号: 3111620-80-2
研究分野:  

Cancer

XJ-4-85 is a covalent activator and precursor compound targeting PFKL (EC50=56 μM in human PFKL). XJ-4-85 activates glycolysis, increases FBP production and glycolytic flux, and enhances LPS-stimulated proinflammatory cytokine release in macrophages. XJ-4-85 causes long-chain acylcarnitine accumulation, metabolic stress, and cytotoxicity through the release of the active payload XJ-4-119 targeting CPT2. XJ-4-85 exhibits broad and selective cytotoxicity across multiple cancer cell lines and is useful for melanoma research .
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製品番号: HY-30215R
CAS 番号: 13748-90-8
別名: (S)-2-Hydroxy-4-methylpentanoic acid (Standard)
(S)-Leucic acid (Standard) ((S)-2-Hydroxy-4-methylpentanoic acid (Standard)) is the analytical standard of (S)-Leucic acid (HY-30215). This product is intended for research and analytical applications. (S)-Leucic acid ((S)-2-Hydroxy-4-methylpentanoic acid) is an α-hydroxy acid found in the fermentation products of Bacillus granulobacter pectinovorum. (S)-Leucic acid is an isomer of Leucic acid (HY-30216A) and a leucine metabolite. (S)-Leucic acid acts as a D-unit subunit precursor in the biosynthesis of cryptophycins in the Nostoc cyanobacterial symbiont. (S)-Leucic acid is used in metabolism-related studies .
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製品番号: HY-B0151R
CAS 番号: 145-13-1
別名: 3β-Hydroxy-5-pregnen-20-one (Standard)
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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製品番号: HY-B0215S1
別名: N-Acetylcysteine-15N; N-Acetyl-L-cysteine-15N; NAC-15N
Acetylcysteine- 15N (N-Acetylcysteine- 15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
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製品番号: HY-N0411S4
CAS 番号: 301150-50-5
別名: Provitamin A-13C10; beta-Carotene-13C10
β-Carotene- 13C10 (Provitamin A- 13C10) is the 13C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
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製品番号: HY-N3677
CAS 番号: 14351-29-2
Dammarenediol II is a ginsenoside precursor . Dammarenediol II reduces the activity of O-GlcNAc transferase (OGT) and downregulates the global O-GlcNAcylation level. Dammarenediol II inhibits the phosphorylation of Akt, mTOR and GSK3β. Dammarenediol II inhibits human carboxylesterase activity, VEGF-induced ROS production, stress fiber formation and vascular endothelial cadherin disruption. Dammarenediol II promotes cell apoptosis (apoptosis), increases the levels of cleaved PARP1 and p53, and inhibits retinal microvascular leakage. Dammarenediol II can be used in studies related to liver cancer and diabetic retinopathy .
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製品番号: HY-N7389A
CAS 番号: 103301-73-1
GDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG) .
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製品番号: HY-N7504
CAS 番号: 905954-18-9
Isopsoralenoside is a benzofuran glycoside and coumarin-derived compound. Isopsoralenoside exists in the dried mature fruits of Psoralea corylifolia L., and acts as a metabolite precursor, toxicant and inducer, with estrogen-like, osteoblast proliferation-promoting, anti-tumor and antibacterial activities. Isopsoralenoside can be deglycosylated by intestinal flora to form isopsoralen. Isopsoralenoside induces oocyte death in zebrafish, activates oxidative stress and cell death-related pathways in zebrafish follicles, and is the main effector substance responsible for the reproductive toxicity induced by Fructus Psoraleae. Isopsoralenoside can be used in studies related to reproductive toxicity (ovarian dysfunction, follicular atresia, impaired fertility) .
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製品番号: HY-N9934R
CAS 番号: 2922-42-1
別名: 3-DHS (Standard); 5-Dehydroshikimic acid (Standard)
(-)-3-Dehydroshikimic acid (Standard) (3-DHS (Standard)) is the analytical standard of (-)-3-Dehydroshikimic acid (HY-N9934). This product is intended for research and analytical applications. (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions .
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製品番号: HY-P11864
研究分野:  

Cancer

DOTA-SMIC-1014 is a DOTA chelator-conjugated precursor of the c-Met-targeting peptide SMIC-1014 (HY-P11863). DOTA-SMIC-1014 binds to the extracellular domain of c-Met (Kd = 42.83 nM). After radiolabeling to [ 68Ga]Ga-SMIC-1014, DOTA-SMIC-1014 acts as a positron emission tomography (PET) probe that achieves specific tumor uptake in xenografts and functions as a diagnostic probe targeting c-Met. SMIC-1014 can be used in research related to colon cancer, hepatocellular carcinoma, and prostate cancer .
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