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Cat. No.: HY-180306

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Fluoroestradiol

Fluoroestradiol is an Estrogen receptor PET imaging tracer precursor. Fluoroestradiol, when radiolabeled with ¹⁸F, can be used as an Estrogen receptor PET imaging tracer. ¹⁸F-Fluoroestradiol exhibits the highest uptake selectivity and target-to-background ratio among
several 18F-labeled estrogens. ¹⁸F-Fluoroestradiol has demonstrated Estrogen receptor expression in normal brain tissues and in meningiomas. ¹⁸F-Fluoroestradiol can quantify regional Estrogen receptor expression in breast cancer. ¹⁸F-Fluoroestradiol has potential applications in assessing and monitoring heterogeneity in ovarian cancer.

For research use only. We do not sell to patients.

CAS No.: 84693-92-5
Formula: C₁₈H₂₃FO₂
Molecular Weight:290.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Fluoroestradiol Chemical Structure

CAS No.: 84693-92-5

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Biological Activity

Description

All Estrogen Receptor/ERR Isoforms :

All Radionuclide-Drug Conjugates (RDCs) Isoforms :

Chemical Information

CAS No. 84693-92-5
Molecular Weight 290.38
Formula C₁₈H₂₃FO₂
SMILES

C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(C[C@H](F)[C@@H]2O)[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liao GJ, et al. 18F-Fluoroestradiol PET: Current Status and Potential Future Clinical Applications. J Nucl Med. 2016;57(8):1269-1275. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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Fluoroestradiol

All Estrogen Receptor/ERR Isoforms

All Radionuclide-Drug Conjugates (RDCs) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Fluoroestradiol Related Classifications

HY-180306 Related Classifications