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1,3,5-Tricaffeoylquinic acid

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1,3,5-Tricaffeoylquinic acid
1,3,5-Tricaffeoylquinic acid
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Cat. No.: HY-N6926
CAS No.: 1073897-80-9
Category:  

Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Plants Disease Research Fields

Target:  

HIV Apoptosis Caspase VEGFR ERK PI3K Akt mTOR PARP

1,3,5-Tricaffeoylquinic acid acts as an angiogenesis inhibitor and apoptosis inducer, and exhibits anti-HIV activity. 1,3,5-Tricaffeoylquinic acid inhibits the phosphorylation of VEGFR2, ERK, PI3K, Akt and mTOR in the angiogenesis signaling pathway. 1,3,5-Tricaffeoylquinic acid regulates apoptosis-related proteins, upregulates the levels of activated caspase-8, Bax, activated PARP and caspase-3/9, while downregulates the level of Bcl-2. 1,3,5-Tricaffeoylquinic acid inhibits tube formation and shows cytotoxicity against ovarian cancer cells. 1,3,5-Tricaffeoylquinic acid can be used in studies related to ovarian cancer .
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