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Results for "

3MST

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (1) Hippo (MST) (3) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1) Metabolic Disease (2)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128206

I3MT-3 5 Publications Verification HMPSNE	Hippo (MST)	Metabolic Disease
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC₅₀=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST .

HY-164595

IHMT-MST1-39	Hippo (MST) Apoptosis AMPK	Metabolic Disease
IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC₅₀ of 42, 109, 286, 159 nM for MST1, MST2, *MST3, MST4*. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 can be used for the studies of type 1 diabetes (T1D) and type 2 diabetes (T2D) .

HY-114804

BRD2577	Hippo (MST)	Cancer
BRD2577 is a selective mercaptopyruvate sulfurtransferase (3-MST) inhibitor with an IC₅₀ of 9.9 μM. BRD2577 inhibits H₂S production in colon carcinoma cells. BRD2577 exhibits weak to no significant inhibitory effect on colon cancer cell proliferation and mitochondrial activity. BRD2577 can be used for the research of colon cancer .

HY-RS20774

Mpst Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mpst Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mpst gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mpst Mouse Pre-designed siRNA Set A Mpst Mouse Pre-designed siRNA Set A

Species:	Human (2)
Tag:	His (1) GST (1)
Source:	Sf9 insect cells (1) E. coli (1)

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HY-P702750

	MST3/STK24 Protein, Human (Active, sf9, GST) STK24; serine/threonine kinase 24; MST3; STK3; MST3B; STE20; HEL-S-95	Human	Sf9 insect cells
	MST3/STK24 is a serine/threonine protein kinase that induces apoptosis in response to stress and caspase activation. It mediates oxidative stress-induced cell death by regulating the phosphorylation of JNK1-JNK2 and p38 during oxidative stress. MST3/STK24 Protein, Human (sf9, GST) is the recombinant human-derived MST3/STK24, expressed by Sf9 insect cells, with GST labeled tag.

HY-P702744

	MST1/STK4 Protein, Human (His) STK4; serine/threonine kinase 4; serine/threonine-protein kinase 4; kinase responsive to stress 2; KRS2; mammalian sterile 20 like 1; MST1; yeast Ste20 like; YSK3; MST-1; STE20-like kinase MST1; mammalian sterile 20-like 1; mammalian STE20-like protein kinase 1; serine/threonine-protein kinase Krs-2; dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)); DKFZp686A2068	Human	E. coli
	MST1/STK4 protein is a stress-activated kinase that is critical in the Hippo signaling pathway and can induce apoptosis and regulate hepatocyte proliferation. Cleaved MST1/STK4 enters the nucleus, causing chromatin condensation and DNA fragmentation. MST1/STK4 Protein, Human (His) is the recombinant human-derived STK4, expressed by E. coli, with His labeled tag.

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Host:	Mouse (1) Rabbit (3)
Reactivity:	Human (4) Rat (3) Mouse (4) Hamster (2)
Application:	IHC-P (3) ICC/IF (1) IP (4) WB (4)
Isotype:	IgG (3) IgG1 (1)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80230

	STK3/MST-2 Antibody (YA282) MST-2; STK3; KRS1; MST2	WB, IHC-P, IP	Human, Mouse
	STK3/MST-2 Antibody (YA282) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STK3/MST-2.

HY-P82338

	STK3/MST-2Antibody (YA2083) STK3; Mess1; MST-2; MST2; Serine/threonine kinase 3; KRS1; STE20-like kinase MST2	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	STK3/MST-2Antibody (YA2083) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STK3/MST-2.

HY-P82338A

	STK3/MST-2Antibody (YA2083)(PBS only) STK3; Mess1; MST-2; MST2; Serine/threonine kinase 3; KRS1; STE20-like kinase MST2	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	STK3/MST-2Antibody (YA2083) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to STK3/MST-2.

HY-P87295

	MST3 Antibody (YA6978) epididymis secretory protein Li 95 antibody; HEL-S-95 antibody; Mammalian STE20 like protein kinase 3 antibody; Mammalian STE20-like protein kinase 3 antibody; Mammalian STE20-like protein kinase 3 C-terminal antibody; Mammalian STE20-like protein kinase 3 N-terminal antibody; Mammalian sterile 20-like 3 antibody; MST-3 antibody; MST3/C antibody; MST3/N antibody	WB, ICC/IF, IP	Human, Mouse, Rat
	MST3 Antibody (YA6978) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MST3.

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Mpst Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Mpst Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mpst gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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