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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
ALDH1L2
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "ALDH1L2" in MCE Product Catalog:
3
3 Cited Publications
Art. -Nr.: HY-W011094
CAS. Nr.: 1477-57-2
Target:
Forschungsgebiete:
Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
2
2 Cited Publications
Synonyms: ALDH1Ai 673A
Forschungsgebiete:
ALDH1A inhibitor 673A is an ALDH1A inhibitor with IC50s of 246 nM (ALDH1A1), 230 nM (ALDH1A2), 348 nM (ALDH1A3), respectively. ALDH1A inhibitor 673A has little or no inhibitory effect on other ALDH family members. ALDH1A inhibitor 673A induces necroptotic ovarian cancer stem-like cells (CSCs) death. ALDH1A inhibitor 673A induces DNA double stand breaks in cancer cells. ALDH1A inhibitor 673A can be used for the study of ovarian cancer .
1
1 Cited Publications
Target:
Forschungsgebiete:
ALDH3A1-IN-3 (CB29) is a selective inhibitor of ALDH3A1, with a Ki value of 4.7 μM and an IC50 value of 16 μM. ALDH3A1-IN-3 has no inhibitory potential on the in vitro activity of ALDH1A1, ALDH1A2, ALDH1A3, ALDH1B1, or ALDH2. ALDH3A1-IN-3 can be used in cellular oxidation and cancer research .
1
1 Cited Publications
Target:
Forschungsgebiete:
CM010 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM010 does not inhibit any of the other ALDH family members. CM010 can regulate metabolism and has anti-cancer activity .
Art. -Nr.: HY-RS00567
Target:
Forschungsgebiete:
ALDH1L2 Human Pre-designed siRNA Set A contains three designed siRNAs for ALDH1L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: N42
Target:
Forschungsgebiete:
FSI-TN42 (N42) is a selective, orally active and irreversible ALDH1A1 inhibitor with an IC50 of 23 nM. FSI-TN42 shows 800-fold more potent against ALDH1A1 than ALDH1A2 (IC50
Target:
Forschungsgebiete:
ALDH1A2-IN-1 is an active site-directed reversible ALDH1A2 inhibitor (IC50=0.91 μM; Kd=0.26 μM) with several hydrophobic interactions .
Art. -Nr.: HY-W011094R
CAS. Nr.: 1477-57-2
Forschungsgebiete:
Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
Art. -Nr.: HY-139032
CAS. Nr.: 2204230-40-8
Target:
Forschungsgebiete:
CM121 is an active site-directed reversible ALDH1A2 inhibitor (IC50=0.54 μM；Kd=1.1 μM) with a variety of hydrophobic interactions .
Art. -Nr.: HY-158026
Target:
Forschungsgebiete:
ALDH1A1-IN-5 (compound 25) is a potent aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with EC50 value of 83, 45, 43 µM for ALDH1A1, ALDH1A2, ALDH1A3, respectively. ALDH1A1-IN-5 has the potential for the research of high-grade serous ovarian cancer (HGSOC) .
Art. -Nr.: HY-RS00563
Target:
Forschungsgebiete:
ALDH1A2 Human Pre-designed siRNA Set A contains three designed siRNAs for ALDH1A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS17028
Target:
Forschungsgebiete:
Aldh1a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aldh1a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS23472
Target:
Forschungsgebiete:
Aldh1a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Aldh1a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
