17 Results for "

ALF

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "ALF" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1131
CAS No.: 826-36-8
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .
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1 Cited Publications
Cat. No.: HY-N1131A
CAS No.: 33973-59-0
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) hydrochloride is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .
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1 Cited Publications
Cat. No.: HY-N1131B
CAS No.: 10581-38-1
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone monohydrate
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats .
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Cat. No.: HY-110036
CAS No.: 180002-83-9
Purity:  99.12%
Synonyms: L768242
GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values ​​of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values ​​of 16.1 μM and 4772 nM for CB1. GW-405833 also exhibits non-competitive CB1 antagonist, exerting its analgesic and and anti-inflammatory effect through a CB1 receptor (rather than CB2) dependent mechanism. GW-405833 can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
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Cat. No.: HY-N1131S
CAS No.: 52168-48-6
Synonyms: 2,2,6,6-Tetramethyl-4-piperidone-d17
Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats .
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Cat. No.: HY-P99138

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse IL-1a Antibody (ALF-161) is an anti-mouse IL-1a IgG1 monoclonal antibody. Anti-Mouse IL-1a Antibody (ALF-161) can inhibit CD8 + T cell response by blocking IL-1a signaling. Anti-Mouse IL-1a Antibody (ALF-161) can reversibly transform myeloid cell expansion and improve T cell function. Anti-Mouse IL-1a Antibody (ALF-161) can be used for researches on immune response and cancer such as breast cancer .
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Cat. No.: HY-110036A
CAS No.: 1202865-22-2
Purity:  99.59%
Synonyms: L768242 hydrochloride
GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values ​​of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values ​​of 16.1 μM and 4772 nM for CB1. GW405833 hydrochloride also exhibits non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor (rather than CB2) dependent mechanism. GW405833 hydrochloride can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 hydrochloride inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF) .
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Cat. No.: HY-154802
CAS No.: 2307311-19-7
Research Areas:  

Cancer

TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2 . TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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Cat. No.: HY-163079
Target:  

FAP

Research Areas:  

Cancer

AlF-PD-FAPI has affinity for FAP , with the IC50 of 0.13 nM, and shows a specific uptake, high internalized fraction, and low cellular efflux in vitro. AlF-PD-FAPI can be used as FAP-targeting tracer .
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Cat. No.: HY-D2334
AlF-NOTA-c-d-VAP is a peptide positron emission tomography (PET) probe that used for targeted tumor imaging of GRP78. AlF-NOTA-c-d-VAP demonstrates high stability in vitro and in vivo .
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Cat. No.: HY-RS18890
Research Areas:  

Others

Afm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Afm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00433
Research Areas:  

Others

AFM Human Pre-designed siRNA Set A contains three designed siRNAs for AFM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-177809
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

aptTNF-α sodium is a TNF-α-targeting aptamer that has tissue protective effect and systemic anti-inflammatory effect upon acute tissue injury using the mouse acute lung injury (ALI) and acute liver failure (ALF) models.
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Cat. No.: HY-P70036
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuAfamin, His; Afamin; AFM; ALB2; ALB2alpha-Alb; ALBA; ALBAalpha-albumin; ALF; Alpha-Alb; Alpha-albumin
Species:  
Source:  
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Cat. No.: HY-P70036B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuAfamin, His; Afamin; AFM; ALB2; ALB2alpha-Alb; ALBA; ALBAalpha-albumin; ALF; Alpha-Alb; Alpha-albumin
Species:  
Source:  
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Cat. No.: HY-P11486
NOTA-RHAU18 is a conjugate of the chelator NOTA and the peptide RHAU18. NOTA-RHAU18 can be used to synthesize the radiolabeled peptide probe [ 18F]AlF-NOTA-RHAU18. [ 18F]AlF-NOTA-RHAU18 targets mitochondrial DNA G4. [ 18F]AlF-NOTA-RHAU18 can be used to visualize and detect solid tumors in homozygous mice. [ 18F]AlF-NOTA-RHAU18 can also be used in PET imaging studies .
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Cat. No.: HY-P11859
Research Areas:  

Cancer

NP1 is a NOTA-chelated linear precursor based on the ROR1-targeting peptide. After labeling with [ 18F]AlF, NP1 yields [ 18F]AlF-NP1, a PET imaging probe with excellent ROR1 specificity (KD = 141.7 nM), rapid tumor uptake and high target-to-background ratio, which is suitable for non-invasive visualization of various ROR1-overexpressing tumors .
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