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Results for "

APOL2

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS00854
    APOL2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    APOL2 Human Pre-designed siRNA Set A contains three designed siRNAs for APOL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    APOL2 Human Pre-designed siRNA Set A
    APOL2 Human Pre-designed siRNA Set A
  • HY-RS26875
    Apol2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Apol2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Apol2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Apol2 Rat Pre-designed siRNA Set A
    Apol2 Rat Pre-designed siRNA Set A
  • HY-N13201
    12-Deoxyphorbol 13-palmitate

    		Apoptosis CDK Cancer
    12-Deoxyphorbol 13-palmitate is a traditional Chinese medicine monomer with antitumor activity that can be isolated from the root of Euphorbia fischeriana. 12-Deoxyphorbol 13-palmitate induces gastric cancer cell cycle arrest and apoptosis by regulating key cell cycle regulators such as cyclin B、cyclin A and CDC2. In addition, 12-Deoxyphorbol 13-palmitate can significantly weaken APOL2–SERCA2–PERK–HES1 signaling and slow liver fibrosis by targeting APOL2 [2].
    12-Deoxyphorbol 13-palmitate
  • HY-N11736
    12-O-Tiglyl-phorbol 13-dodecanoate

    		Collagen Metabolic Disease
    12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α-smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana, and it is applicable to the research of hepatic fibrosis .
    12-O-Tiglyl-phorbol 13-dodecanoate

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