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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
ASCL1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "ASCL1" in MCE Product Catalog:
Cat. No.: HY-155218
CAS No.: 2488892-09-5
TMX-2172 is a selective bivalent cereblon-recruiting PROTAC-based dual CDK2 and CDK5 degrader with IC50 values of 6.5 nM and 6.8 nM, respectively. TMX-2172 shows selectivity for CDK2 and CDK5 over other cell cycle CDKs (CDK1, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9). TMX-2172 inhibits CDK2/CDK5 enzymatic activity, induces their proteasomal degradation, reduces ASCL1 protein levels and half-life, induces cancer cell death, and exerts antiproliferative effects. TMX-2172 can be used for the research of ovarian cancer and small cell lung cancer [1] .
Cat. No.: HY-174778
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Human ASCL1 mRNA encodes the human achaete-scute family bHLH transcription factor 1 (ASCL1) protein, a member of the basic helix-loop-helix (BHLH) family. ASCL1 plays a role in the neuronal commitment and differentiation, and in the generation of olfactory and autonomic neurons.
Cat. No.: HY-RS01078
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ASCL1 Human Pre-designed siRNA Set A contains three designed siRNAs for ASCL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21486
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Ascl1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ascl1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28004
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Ascl1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ascl1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991871
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Cat. No.: HY-P81381A
Synonyms: ASCL1; ASH1, BHLHA46; HASH1; Achaete-scute homolog 1; ASH-1; hASH1 ; Class A basic helix-loop-helix protein 46
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
