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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
Acidic nucleoplasmic DNA-binding protein 1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Acidic nucleoplasmic DNA-binding protein 1" in MCE Product Catalog:
Cat. No.: HY-P701614
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA binding protein 1; AND-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; AND1; CTF4, Chromosome Transmission Fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:
Human
Source:
HEK293
Cat. No.: HY-162896
CAS No.: 3029132-46-2
Target:
Research Areas:
And1 degrader 1 is an acidic nucleoplasmic DNA-binding protein 1 (And1) molecular glue-like degrader. And1 degrader 1 binds to the WD40 domain of And1 in a 'V' conformation to induce And1 degradation via the ubiquitin-proteasome pathway. And1 degrader 1 exhibits antiproliferative activity via synthetic lethal interaction with a PARP1 inhibitor to inhibit proliferation of cancer cells. And1 degrader 1 can be used for the research of non-small cell lung cancer (NSCLC) .
Cat. No.: HY-P701615
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WDHD1; WD Repeat And HMG-Box DNA binding protein 1; AND-1; CHTF4; CTF4; WD Repeat And HMG-Box DNA-binding protein 1; Acidic nucleoplasmic DNA-binding protein 1; AND1; CTF4, Chromosome Transmission Fidelity Factor 4 Homolog (S. Cerevisiae); CTF4, Chromosom
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
