9 Results for "

Alisol C

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Alisol C" in MCE Product Catalog:

5
Alisol A
Alisol A
0 Images
5 Cited Publications
Cat. No.: HY-N0853
CAS No.: 19885-10-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

AMPK Acetyl-CoA Carboxylase PPAR MMP Interleukin Related

Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
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1
Alisol B
Alisol B
0 Images
1 Cited Publications
Cat. No.: HY-N0805A
CAS No.: 18649-93-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Metabolic Disease Plants Alismataceae Disease Research Fields

Target:  

Epoxide Hydrolase CaMK Autophagy Apoptosis

Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer .
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1
Alisol A 24-acetate
Alisol A 24-acetate
0 Images
1 Cited Publications
Cat. No.: HY-N0853A
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate; Alisol A monoacetate
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

AMPK Carnitine Palmitoyltransferase (CPT) Acyltransferase Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase Bcl-2 Family PPAR Nuclear Factor of activated T Cells (NFAT) PI3K Akt PKA ERK Apoptosis Autophagy

Alisol A 24-acetate (Alisol A monoacetate) is an orally active derivative of protostane-type tetracyclic triterpenoid. Alisol A 24-acetate upregulates the expression of adiponectin, AMPKα, CPT1, and ACOX1; downregulates the expression of SREBP-1c, ACC, FAS, Bcl-2, Bcl-xl, PPAR-γ, perilipin A, and NFATc1; inhibits the activity of PI3K/Akt/mTOR and HMGR; and activates the PKA and ERK signaling pathways. Alisol A 24-acetate regulates cell apoptosis (apoptosis), autophagy (Autophagy, hepatic lipid accumulation, inflammatory response, neuroprotection, MRSA membrane integrity, and osteoclast differentiation. Alisol A 24-acetate can be used in research related to non-alcoholic fatty liver disease, nephrotoxicity, obesity, global cerebral ischemia-reperfusion injury, bacterial infection, and osteoporosis .
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1
5-Methyltetrahydrofolic acid (Standard)
5-Methyltetrahydrofolic acid (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-113046R
CAS No.: 134-35-0
Synonyms: 5-Methyl THF (Standard); 5-MTHF (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.
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Alisol C
Alisol C
0 Images
Cat. No.: HY-N6570
CAS No.: 30489-27-1
Category:  

Triterpenes Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae

Target:  

Others

Alisol C is a triterpenoid that can be found in the tuber of Alisma orientale (Sam.) Juzep .
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Alisol C 23-acetate
Alisol C 23-acetate
0 Images
Cat. No.: HY-N0856
CAS No.: 26575-93-9
Synonyms: 23-O-AcetylAlisol C; Alisol C monoacetate
Category:  

Cardiovascular Disease Triterpenes Alisma plantago-aquatica Linn. Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae Disease Research Fields

Target:  

Others

Alisol C 23-acetate, a natural product extracted from Alisma orinentale, can significantly and strongly inhibit DTH response after oral administration.
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Alisol C 23-acetate (Standard)
Alisol C 23-acetate (Standard)
0 Images
Cat. No.: HY-N0856R
CAS No.: 26575-93-9
Synonyms: 23-O-AcetylAlisol C (Standard); Alisol C monoacetate (Standard)
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae

Target:  

Reference Standards Others

Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.
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Alisol A (Standard)
Alisol A (Standard)
0 Images
Cat. No.: HY-N0853R
CAS No.: 19885-10-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards AMPK Acetyl-CoA Carboxylase PPAR MMP Interleukin Related

Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
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Alisol B (Standard)
Alisol B (Standard)
0 Images
Cat. No.: HY-N0805AR
CAS No.: 18649-93-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards Epoxide Hydrolase CaMK Autophagy Apoptosis

Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.
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