1 Result for "

Amorphigenin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Amorphigenin" in MCE Product Catalog:

Cat. No.: HY-116640
CAS No.: 4208-09-7
Amorphigenin is a trothotenone compound. Amorphigenin inhibits osteoclast differentiation by suppressing the expression of c-Fos and NFATc1 in activated T cells. Amorphigenin degrades melanosome proteins by activating the AMPK-dependent autophagy pathway, but not in dependence of the mTOR pathway. Amorphigenin significantly protects bone mass and reduces bone erosion in a mouse model of inflammatory bone loss. Amorphigenin can be used to study inflammatory bone diseases, postmenopausal osteoporosis, and skin pigmentation disorders .
loading...
    loading...