10 Results for "

Angelate

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Angelate" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B0719
CAS No.: 75567-37-2
Synonyms: Ingenol 3-Angelate; PEP005
Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
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1
1 Cited Publications
Cat. No.: HY-N4322
CAS No.: 130848-06-5
Decursinol angelate acts as a PKC activator and GDH inhibitor, with an IC50 of 1.432 μM against human GDH. Decursinol angelate activates PKC, downregulates PKCα and PKCβII isoforms, and exerts cytotoxic activity against cancer cells. Decursinol angelate binds to GDH and inhibits its enzymatic activity. Decursinol angelate inhibits VEGF-induced autophosphorylation of VEGFR2, downstream p42/44 ERK and JNK-MAPK signaling pathways, as well as the angiogenesis process. Decursinol angelate is applicable to research related to cancer and leukemia .
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Cat. No.: HY-N0870
CAS No.: 87980-68-5
Synonyms: Ingenol 5,20-acetonide 3-Angelate; Ingenol 3-Angelate 5,20-acetonide
Ingenol-5,20-acetonide-3-O-angelate is a natural compound.
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Cat. No.: HY-161103
CAS No.: 6247-64-9
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Angeloyl-CoA is a CoA-activated form of angelic acid and has anticancer activity. Angeloyl-CoA can be produced based on yeast .
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Cat. No.: HY-N1684
CAS No.: 75567-38-3
20-Deoxyingenol 3-angelate (DI3A) increases degranulation and interferon-gamma secretion of NK cells. 20-Deoxyingenol 3-angelate enhances NK cell tumoricidal activity .
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Cat. No.: HY-N13106
CAS No.: 60419-37-6
Camelliagenin A 22-angelate (compound 5) is a triterpenoid isolated from the bark of birch .
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Cat. No.: HY-N4322R
CAS No.: 130848-06-5
Decursinol angelate (Standard) is the analytical standard of Decursinol angelate. This product is intended for research and analytical applications. Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities .
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Cat. No.: HY-N0868
CAS No.: 82425-35-2
Synonyms: Euphorbia factor Pe1
20-O-Acetylingenol-3-angelate is a natural compound.
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Cat. No.: HY-B0719R
CAS No.: 75567-37-2
Synonyms: Ingenol 3-Angelate (Standard); PEP005 (Standard)
Ingenol Mebutate (Standard) is the analytical standard of Ingenol Mebutate. This product is intended for research and analytical applications. Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
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Cat. No.: HY-N9162
CAS No.: 72229-39-1
Target:  

Others

2α-Hydroxyeupatolide 8-O-angelate is a Sesquiterpenoids product that can be isolated from the herbs of Eupatorium chinense var. tozanense. .
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