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Arabidopsis seedlings

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By Targets:	Antibiotic (7) Bacterial (7) DNA/RNA Synthesis (7) Drug Derivative (1) Endogenous Metabolite (4) Glycosidase (1) Glycosyltransferase (1) Interleukin Related (1) Isotope-Labeled Compounds (4) Monoamine Oxidase (3) Phytohormone (3) Proton Pump (1) Reference Standards (3)
By Research Areas:	Cancer (4) Infection (10) Inflammation/Immunology (1) Metabolic Disease (9) Neurological Disease (3)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008566

Norharmane Norharman; β-Carboline	Monoamine Oxidase Endogenous Metabolite	Infection Neurological Disease Cancer
Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-117660

Lincomycin 5 Publications Verification U-10149	Antibiotic Bacterial DNA/RNA Synthesis	Infection Metabolic Disease
Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-N10455

24-Epicastasterone 2 Publications Verification 24-epi-Castasterone	Drug Derivative	Others
24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings .

HY-B0417A

Lincomycin hydrochloride 5 Publications Verification U10149A	DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin hydrochloride (U10149A) is an orally active lincosamide antibiotic. Lincomycin hydrochloride binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-B1358

Lincomycin hydrochloride monohydrate 5 Publications Verification U-10149 hydrochloride monohydrate	DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin (U-10149) hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-B1918

(+)-Bornyl acetate	Interleukin Related	Others
(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings .

HY-121161C

(2R,3S)-Brassinazole	Phytohormone	Metabolic Disease
Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism .

HY-179028

DHGA5 exo-16,17-Dihydro-gibberellin A5-13-acetate	Phytohormone	Others
DHGA5 (exo-16,17-Dihydro-gibberellin A5-13-acetate) is a GA3β-hydroxylase (OsGA3ox2) inhibitor. DHGA5 inhibits Arabidopsis root growth with an IC₅₀ of 97 μM. DHGA5 also suppresses the elongation of rice second leaf sheath. DHGA5 can alleviate oxidative damage to Arabidopsis seedlings under NaCl salt stress and reduce the accumulation of superoxide anion .

HY-163279

Fluopipamine	Glycosidase	Others
Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC₅₀ of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings .

HY-162466

ABA receptor agonist 1	Proton Pump	Others
ABA receptor agonist 1 (compound 4c) is a receptor agonist for abscisic acid (ABA). ABA receptor agonist 1 can inhibit seed germination and seedling growth of Arabidopsis and rice, stomatal closure and drought resistance of wheat and soybean .

HY-117660S

Lincomycin-d3 U-10149-d₃	Isotope-Labeled Compounds DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin-d₃ (U-10149-d₃) is the deuterium labeled Lincomycin. Lincomycin is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-117660R

Lincomycin (Standard) U-10149 (Standard)	Reference Standards DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin (U-10149) (Standard) is the analytical reference standard of Lincomycin (HY-117660). This product is used for research and analytical applications. Lincomycin is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-B1358R

Lincomycin hydrochloride monohydrate (Standard) U-10149 hydrochloride monohydrate (Standard)	Reference Standards DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin (U-10149) hydrochloride monohydrate (Standard) is the analytical standard of Lincomycin hydrochloride monohydrate (HY-B1358). This product is intended for research and analytical applications. Lincomycin hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-W700241

Norharman-d7	Isotope-Labeled Compounds Monoamine Oxidase Endogenous Metabolite	Infection Neurological Disease Cancer
Norharman-d₇ is deuterium labeled Norharmane. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-W008566R

Norharmane (Standard) Norharman (Standard); β-Carboline (Standard)	Reference Standards Monoamine Oxidase Endogenous Metabolite	Infection Neurological Disease Cancer
Norharmane (Standard) is the analytical standard of Norharmane. This product is intended for research and analytical applications. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-182408

Endosidin7	Glycosyltransferase	Others
Endosidin7 is a specific inhibitor for plant callose deposition during cytokinesis. Endosidin7 inhibits cytokinesis-specific callose deposition at the cell plate, disrupts cell plate maturation, and alters localization of cell plate-associated proteins during late cell plate development. Endosidin7 slows root growth and induces formation of cell wall stubs in Arabidopsis thaliana seedlings .

HY-179025

GA3ox-IN-1	Phytohormone	Others
GA3ox-IN-1 (Compound 10e) is a GA3β-hydroxylase (GA3ox) inhibitor. GA3ox-IN-1 inhibits Arabidopsis root growth with an IC₅₀ of 90 μM. GA3ox-IN-1 also suppresses the elongation of rice second leaf sheath. GA3ox-IN-1 can alleviate oxidative damage to Arabidopsis seedlings under NaCl salt stress and reduce the accumulation of superoxide anion .

HY-N9181

4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol	Others	Others
4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol is a phytotoxic polyacetylene compound. 4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol can be isolated from the roots and root exudates of Acroptilon repens. It exhibits phytotoxicity and reduces the root length of lettuce .

HY-117660S1

Lincomycin-13C,d3 U-10149-¹³C,d₃	Isotope-Labeled Compounds DNA/RNA Synthesis Antibiotic Bacterial	Infection Metabolic Disease
Lincomycin- ¹³C,d₃ (U-10149- ¹³C,d₃) is the deuterium and ¹³C-labeled Lincomycin (HY-117660). Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-W008566S

Norharmane-13C Norharman-¹³; β-Carboline-¹³C	Isotope-Labeled Compounds	Cancer
Norharmane- ¹³C (Norharman- ¹³C) is the ¹³C-labeled Norharmane (HY-W008566). Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-W750419

cis-9-Hexadecenoylcarnitine inner salt Palmitoleoylcarnitine (C16:1)	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
cis-9-Hexadecenoylcarnitine inner salt (Palmitoleoylcarnitine (C16:1)) is a long-chain acylcarnitine controlling fatty acid metabolism and mitochondrial function. cis-9-Hexadecenoylcarnitine inner salt accumulates in colorectal cancer cells. cis-9-Hexadecenoylcarnitine inner salt exists in plants and mediates lipid anabolic development. cis-9-Hexadecenoylcarnitine inner salt acts as a metabolic marker for type 1 diabetes and inflammatory bowel disease plasma. cis-9-Hexadecenoylcarnitine inner salt can be used for research on diabetes, metabolism, and inflammatory bowel disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008566

Norharmane Norharman; β-Carboline	Neurological Disease Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Biological Pesticide Research Indole Alkaloids Agricultural Research Infection Alkaloids Microorganisms Disease Research Fields Source Classification Cancer	Monoamine Oxidase Endogenous Metabolite
Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-117660

Lincomycin 5 Publications Verification U-10149	Infection Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Disease Research Fields Source Classification	Antibiotic Bacterial DNA/RNA Synthesis
Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-N10455

24-Epicastasterone 2 Publications Verification 24-epi-Castasterone	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Brassinolide Phytohormone Disease Research Fields Source Classification Agricultural Research	Drug Derivative
24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings .

HY-B0417A

Lincomycin hydrochloride 5 Publications Verification U10149A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics Plant agriculture research Source Classification	DNA/RNA Synthesis Antibiotic Bacterial
Lincomycin hydrochloride (U10149A) is an orally active lincosamide antibiotic. Lincomycin hydrochloride binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-B1358

Lincomycin hydrochloride monohydrate 5 Publications Verification U-10149 hydrochloride monohydrate	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics Plant agriculture research Source Classification	DNA/RNA Synthesis Antibiotic Bacterial
Lincomycin (U-10149) hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-B1918

(+)-Bornyl acetate	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Other Diseases Hamamelidaceae Plants Disease Research Fields Source Classification Liquidambar formosana Hance	Interleukin Related
(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings .

HY-117660R

Lincomycin (Standard) U-10149 (Standard)	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Source Classification	Reference Standards DNA/RNA Synthesis Antibiotic Bacterial
Lincomycin (U-10149) (Standard) is the analytical reference standard of Lincomycin (HY-117660). This product is used for research and analytical applications. Lincomycin is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-B1358R

Lincomycin hydrochloride monohydrate (Standard) U-10149 hydrochloride monohydrate (Standard)	Structural Classification Microorganisms Antibiotics Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics Plant agriculture research Source Classification	Reference Standards DNA/RNA Synthesis Antibiotic Bacterial
Lincomycin (U-10149) hydrochloride monohydrate (Standard) is the analytical standard of Lincomycin hydrochloride monohydrate (HY-B1358). This product is intended for research and analytical applications. Lincomycin hydrochloride monohydrate is an orally active lincosamide antibiotic. Lincomycin hydrochloride monohydrate binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin hydrochloride monohydrate can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin hydrochloride monohydrate induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-W008566R

Norharmane (Standard) Norharman (Standard); β-Carboline (Standard)	Alkaloids Structural Classification Microorganisms Pyridine Alkaloids Endogenous metabolite Indole Alkaloids Source Classification	Reference Standards Monoamine Oxidase Endogenous Metabolite
Norharmane (Standard) is the analytical standard of Norharmane. This product is intended for research and analytical applications. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-N9181

4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol	Structural Classification Natural Products Indigofera heterantha Wall. ex Brand. Plants Compositae Source Classification	Others
4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol is a phytotoxic polyacetylene compound. 4'-Chloro-1'-(5-penta-1,3-diyn-1-yl-2-thienyl)-but-2'-yn-3'-ol can be isolated from the roots and root exudates of Acroptilon repens. It exhibits phytotoxicity and reduces the root length of lettuce .

Cat. No.	Product Name	Chemical Structure

HY-117660S

Lincomycin-d3
Lincomycin-d₃ (U-10149-d₃) is the deuterium labeled Lincomycin. Lincomycin is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

Lincomycin-d3

Lincomycin-d₃ (U-10149-d₃) is the deuterium labeled Lincomycin. Lincomycin is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice.

HY-W700241

Norharman-d7
Norharman-d₇ is deuterium labeled Norharmane. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

Norharman-d7

Norharman-d₇ is deuterium labeled Norharmane. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-117660S1

Lincomycin-13C,d3
Lincomycin- ¹³C,d₃ (U-10149- ¹³C,d₃) is the deuterium and ¹³C-labeled Lincomycin (HY-117660). Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

Lincomycin-13C,d3

Lincomycin- ¹³C,d₃ (U-10149- ¹³C,d₃) is the deuterium and ¹³C-labeled Lincomycin (HY-117660). Lincomycin (U-10149) is an orally active lincosamide antibiotic. Lincomycin binds to the ribosomes of Gram-positive bacteria to inhibit protein synthesis. Lincomycin can inhibit chloroplast translation, disrupt chloroplast integrity, and activate chloroplast-to-nucleus retrograde signaling in Arabidopsis thaliana seedlings. Lincomycin induces alterations in lipid profiles and liver injury, disrupts blood glucose and insulin levels, and increases growth rate in mice .

HY-W008566S

Norharmane-13C
Norharmane- ¹³C (Norharman- ¹³C) is the ¹³C-labeled Norharmane (HY-W008566). Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

Norharmane-13C

Norharmane- ¹³C (Norharman- ¹³C) is the ¹³C-labeled Norharmane (HY-W008566). Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

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Arabidopsis seedlings

Inhibitors & Agonists

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Isotope-Labeled Compounds

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