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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
51 Results for "
Aripiprazole
" in MedChemExpress (MCE) Product Catalog:
Products (51)
51 Results for "Aripiprazole" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: OPC-14597
Target:
Research Areas:
Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19 .
11
11 Publications Verification
Cat. No.: HY-14546A
CAS No.: 851220-85-4
Synonyms: OPC-14597 monohydrate
Target:
Research Areas:
Aripiprazole (OPC-14597) monohydrate, an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole monohydrate is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole monohydrate can be used for the research of schizophrenia and COVID19 .
11
2
2 Cited Publications
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Research Areas:
Aripiprazole lauroxil, an N-acyloxymethyl proagent of Aripiprazole (HY-14546), is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia and a ligand of dopamine receptor D2R/D4R. Aripiprazole lauroxil is cleaved by body’s enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity.
2
2 Cited Publications
Research Areas:
UNC9994, an analog of Aripiprazole, is a functionally selective β-arrestin-biased dopamine D2 receptor (D2R) agonist with EC50 <10 nM for β-arrestin-2 recruitment to D2 receptors. UNC9994 is simultaneously partial agonists of β-arrestin-2 translocation and antagonists of Gi-regulated cAMP production. Antipsychotic Activity .
1
1 Cited Publications
Synonyms: OPC-14857; DM-14857
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Research Areas:
Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole (HY-14546) and dopamine D2/D3 receptor partial agonist. Dehydroaripiprazole also has certain affinity for serotonin 5-HT1A, 5-HT2A and 5-HT2B receptors. Dehydroaripiprazole has antipsychotic activity equivalent to Aripiprazole .
Cat. No.: HY-W054225
CAS No.: 882880-12-8
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Aripiprazole impurity 31 is an impurity of Aripiprazole.
Cat. No.: HY-14546R
CAS No.: 129722-12-9
Synonyms: OPC-14597 (Standard)
Research Areas:
Aripiprazole (Standard) is the analytical standard of Aripiprazole. This product is intended for research and analytical applications. Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19 .
Synonyms: OPC-14597-d8
Cat. No.: HY-W002108
CAS No.: 553-03-7
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Research Areas:
3,4-Dihydroquinolin-2(1H)-one is a building block, that can be used for synthesis of antipsychotic agent, such as Aripiprazole (HY-14546) or CYP11B2 inhibitors .
Cat. No.: HY-108751R
CAS No.: 1259305-29-7
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Research Areas:
Aripiprazole Lauroxil (Standard) is the analytical standard of Aripiprazole Lauroxil. This product is intended for research and analytical applications. Aripiprazole lauroxil, an N-acyloxymethyl proagent of Aripiprazole (HY-14546), is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia and a ligand of dopamine receptor D2R/D4R. Aripiprazole lauroxil is cleaved by body’s enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity.
Cat. No.: HY-W741839
CAS No.: 573691-13-1
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Research Areas:
Aripiprazole N,N-dioxide is a metabolite of the atypical antipsychotic aripiprazole (HY-14546). It is formed from aripiprazole via oxidation.
Cat. No.: HY-Z2493
CAS No.: 573691-09-5
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Research Areas:
Aripiprazole N-oxide is a metabolite of the atypical antipsychotic Aripiprazole (HY-14546). Aripiprazole N-oxide is formed from aripiprazole by the cytochrome P450 (CYP) isoforms CYP2D6 and CYP3A4.
Cat. No.: HY-143913S
Cat. No.: HY-113575
CAS No.: 1008531-60-9
Synonyms: OPC-14857 hydrochloride; DM-14857 hydrochloride
Target:
Research Areas:
Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole hydrochloride. Dehydroaripiprazole hydrochloride has with antipsychotic activity equivalent to Aripiprazole .
Cat. No.: HY-100665S
CAS No.: 2749328-53-6
Synonyms: OPC-14857-d8; DM-14857-d8
Cat. No.: HY-100665R
CAS No.: 129722-25-4
Synonyms: OPC-14857 (Standard); DM-14857 (Standard)
Target:
Research Areas:
Dehydroaripiprazole (Standard) is the analytical standard of Dehydroaripiprazole. This product is intended for research and analytical applications. Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole (HY-14546) and dopamine D2/D3 receptor partial agonist. Dehydroaripiprazole also has certain affinity for serotonin 5-HT1A, 5-HT2A and 5-HT2B receptors. Dehydroaripiprazole has antipsychotic activity equivalent to Aripiprazole .
Cat. No.: HY-Z6691
CAS No.: 203395-78-2
Synonyms: Aripiprazole Impurity 19
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Research Areas:
Aripiprazole impurity 17 (Aripiprazole Impurity 19) is an impurity of Aripiprazole.
Cat. No.: HY-W027787
CAS No.: 57260-67-0
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Research Areas:
Aripiprazole impurity 9 is an impurity of Aripiprazole.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
