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Results for "

Big-ET-1

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

4

Peptides

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P4159
    Endothelin-1 (1-31) (Human)
    1 Publications Verification

    		 ERK Cardiovascular Disease
    Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) is derived from the selective hydrolysis of big ET-1 by chymase [1].
    Endothelin-1 (1-31) (Human)
  • HY-P4159A
    Endothelin-1 (1-31) (Human) TFA
    1 Publications Verification

    		 ERK Cardiovascular Disease
    Endothelin-1 (1-31) (Human) TFA is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) TFA is derived from the selective hydrolysis of big ET-1 by chymase [1].
    Endothelin-1 (1-31) (Human) TFA
  • HY-P3733
    Big Endothelin-1 (22-38), human

    		Endothelin Receptor Cardiovascular Disease
    Big Endothelin-1 (22-38), human is derived from human, is the 22-38 fragment of Big Endothelin-1 (ET-1) (1-38). Big ET-1 (1-38) is a propeptide of ET-1, which has potent and long-lasting vasoconstrictor effects, equips a specific enzymatic cleavage of the 38 amino acid chain to form ET-1 (1-21) and the C-terminal fragment Big ET-1 (22-38) [1].
    Big Endothelin-1 (22-38), human
  • HY-P991963
    Anti-Big-ET-1 Antibody

    		ERK Others
    Anti-Big-ET-1 Antibody is a humanized monoclonal antibody targeting Big-ET-1. Recommended Isotype Control: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
    Anti-Big-ET-1 Antibody
  • HY-P4159B
    Endothelin-1 (1-31) (Human) acetate

    		ERK Cardiovascular Disease
    Endothelin-1 (1-31) (Human) acetate is a potent vasoconstrictor and hypertensive agent. Endothelin-1 (1-31) (Human) acetate is derived from the selective hydrolysis of big ET-1 by chymase [1].
    Endothelin-1 (1-31) (Human) acetate
  • HY-124234
    TA-0201

    		Endothelin Receptor Cardiovascular Disease
    TA-0201 is a novel orally active, competitive, non-peptide endothelin receptor antagonist. TA-0201 antagonizes the specific binding of [ 125I]ET-1 to cloned human receptors of ETA and ETB with Ki values of 15 pM and 41 nM, respectively. TA-0201 inhibits the pressor response to the exogenous big ET-1 [1].
    TA-0201
  • HY-18211
    CGS 35601

    		Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats [1].
    CGS 35601

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