8 Results for "

Bufalin

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Bufalin" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-N0877
CAS No.: 465-21-4
Bufalin is an active component isolated from Chan Su, acts as a potent Na +/K +-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM, respectively . Anti-cancer activity .
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Cat. No.: HY-N12167
CAS No.: 465-20-3
Category:  

Microorganisms Steroids

Target:  

Others

3-epi-Bufalin (compound 2a) is the microbial transformation product of bufadienolide .
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Cat. No.: HY-178115
MB-Buf is a conjugation of methylene blue (HY-14536) and bufalin (HY-N0877) . MB-Buf can targeting degrade GPX4 upon light activation. MB-Buf can induce cell apoptosis, ferroptosis, and ROS production. MB-Buf can be used for the research of cancer, such as breast cancer .
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Cat. No.: HY-N13080
CAS No.: 4029-65-6
Category:  

Microorganisms Steroids

Target:  

Others

3-Oxo-bufalin is an active compound that can be isolated from cultured toad liver tissue. 3-Oxo-bufalin can be produced through a metabolic pathway, and it is a metabolite of Bufalin (HY-N0877) catalyzed by the stereoselective 3β-dehydrogenase. Bufalin is a Na+/K+-ATPase inhibitor and has anti-tumor activity .
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Cat. No.: HY-N0877R
CAS No.: 465-21-4
Bufalin (Standard) is the analytical standard of Bufalin. This product is intended for research and analytical applications. Bufalin is an active component isolated from Chan Su, acts as a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM, respectively . Anti-cancer activity .
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Cat. No.: HY-164568
CAS No.: 773133-78-1
Target:  

Drug Derivative

Research Areas:  

Cancer

7β,16α-Dihydroxybufalin is a dihydroxylated derivative of bufalin, which exhibits cytotoxicities against cancer cell lines .
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Cat. No.: HY-180430
CAS No.: 1385011-94-8
Target:  

Drug Derivative

Research Areas:  

Cancer

Antitumor agent-208, a Bufalin (HY-N0877) analogue, is a potent and orally active antitumor agent. Antitumor agent-208 exhibits antiproliferative activity against tumor cell line (IC50 =0.30-1.09 nM). Antitumor agent-208 inhibits tumor growth in a MV-4-11 xenograft mouse model. Antitumor agent-208 can be used for cancer research, such as acute myeloid leukemia (AML) and non-small cell lung cancer (NSCLC) .
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Cat. No.: HY-N13079
CAS No.: 36121-84-3
Category:  

Animals Steroids

Target:  

Others

3-Epicinobufagin (compound IX) can be used as an internal standard for the metabolism of Bufalin (HY-N0877), by detecting its content in serum and urine to provide feedback on the corresponding metabolic status .
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