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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
CALR
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "CALR" in MCE Product Catalog:
2
2 Cited Publications
Research Areas:
Necrocide 1, a necrosis by sodium overload (NECSO) inducer, is a selective transient receptor potential melastatin 4 (TRPM4) agonist with an EC50 of 306.3 nM for human TRPM4. Necrocide 1 triggers TRPM4-dependent necrotic cell death through the induction of sodium influx. Necrocide 1 induces hallmarks of immunogenic cell death incurring calreticulin (CALR) exposure, ATP secretion and high mobility group box 1 (HMGB1) release. Necrocide 1 can be used for the study of breast and prostate cancer .
1
Cat. No.: HY-176252
CAS No.: 3055854-78-6
CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells (IC50=0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC .
Cat. No.: HY-RS01847
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CALR Human Pre-designed siRNA Set A contains three designed siRNAs for CALR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01848
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CALR3 Human Pre-designed siRNA Set A contains three designed siRNAs for CALR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20371
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Calr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Calr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17947
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Calr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Calr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24418
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Calr Rat Pre-designed siRNA Set A contains three designed siRNAs for Calr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26881
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Calr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Calr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P706004
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CALR; CALReticulin; CRP55; CALRegulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP
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Cat. No.: HY-109113
CAS No.: 236095-26-4
Synonyms: GPX-150
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Camsirubicin (GPX-150) is a non-cardiotoxic Doxorubicin (HY-15142) analog that selectively targets topoisomerase IIβ. Camsirubicin reduces cell viability and clone formation of MDA-MB-468 breast cancer cells. Camsirubicin increases the exposure of CALR and HSP90 on the cell surface. Camsirubicin can be used for the study of breast cancer .
Cat. No.: HY-P72111
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Autoantigen RO; CALR; CALR protein; CALR_HUMAN; CALRegulin; CALReticulin; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; Epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL S 99n; RO; Sicca syndrome antigen A autoantigen Ro; CALReticulin; ; Sicca syndrome antigen A; SSA
Cat. No.: HY-P71722
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CALRCALReticulin; CRP55; CALRegulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
