2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Camsirubicin

Camsirubicin (GPX-150) is a non-cardiotoxic Doxorubicin (HY-15142) analog that selectively targets topoisomerase IIβ. Camsirubicin reduces cell viability and clone formation of MDA-MB-468 breast cancer cells. Camsirubicin increases the exposure of CALR and HSP90 on the cell surface. Camsirubicin can be used for the study of breast cancer.

For research use only. We do not sell to patients.

Camsirubicin

Camsirubicin Chemical Structure

CAS No. : 236095-26-4

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Camsirubicin Related Antibodies

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Topoisomerase Topo I Topo II DNA gyrase

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Description

Camsirubicin (GPX-150) is a non-cardiotoxic Doxorubicin (HY-15142) analog that selectively targets topoisomerase IIβ. Camsirubicin reduces cell viability and clone formation of MDA-MB-468 breast cancer cells. Camsirubicin increases the exposure of CALR and HSP90 on the cell surface. Camsirubicin can be used for the study of breast cancer[1][2].

IC50 & Target[1]

topoisomerase II beta

 

Clinical Trial
Molecular Weight

528.55

Formula

C27H32N2O9
CAS No.
SMILES

OC1=C(C[C@](CCO)(O)C[C@@H]2O[C@@](O[C@@H](C)[C@H]3O)([H])C[C@@H]3N)C2=C(O)C(C4=N)=C1C(C5=CC=CC(OC)=C45)=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Camsirubicin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Camsirubicin236095-26-4GPX-150GPX150GPX 150TopoisomeraseDoxorubicin Analogtopoisomerase IIβbreast cancernon-cardiotoxicCALRHSP90Inhibitorinhibitorinhibit

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