13 Results for "

CBX7

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "CBX7" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100832
CAS No.: 1872382-47-2
Purity:  99.50%
Research Areas:  

Cancer

UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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2
2 Cited Publications
Cat. No.: HY-119344
CAS No.: 423748-02-1
Purity:  99.81%
Research Areas:  

Cancer

MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a Kd of 27.7 μM. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARF locus in prostate cancer cells .
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Cat. No.: HY-126327A
Purity:  ≥98.0%
Research Areas:  

Cancer

UNC4976 TFA is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 TFA simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
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Cat. No.: HY-126327
CAS No.: 2920299-34-7
Research Areas:  

Cancer

UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
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Cat. No.: HY-RS02014
Research Areas:  

Others

CBX7 Human Pre-designed siRNA Set A contains three designed siRNAs for CBX7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17449
Research Areas:  

Others

Cbx7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cbx7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23905
Research Areas:  

Others

Cbx7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cbx7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-125655
CAS No.: 1872382-50-7
Research Areas:  

Others

UNC-4219 TFA is a negative control for the CBX7-H3 antagonist UNC3866 (HY-100832) and does not interact with CBX7 at high concentrations .
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Cat. No.: HY-100832A
CAS No.: 1872382-48-3
Research Areas:  

Cancer

UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel.
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Cat. No.: HY-P87152
Synonyms: CBX 7 antibody; CBX7 antibody; Chromobox homolog 7 antibody; Chromobox protein homolog 7 antibody;

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human

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Cat. No.: HY-181089
CAS No.: 3124602-03-2
Research Areas:  

Cancer

CBX2-IN-1 is a CBX2 inhibitor with an IC50 of 9.6 μM. CBX2-IN-1 binds the CBX2 chromodomain’s H3K27me3 binding channel, blocks interaction between CBX2 and H3K27me3, and exhibits selective affinity toward CBX2, CBX4, CBX6, CBX7, and CBX8 over CBX1, CBX3, and CBX5. CBX2-IN-1 can be used for the research of prostate cancers .
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Cat. No.: HY-P810761
Synonyms: DER12; ENT2; HNP36; Equilibrative nucleoside transporter 2; 36 kDa nucleolar protein HNP36; Delayed-early response protein 12; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative NBMPR-insensitive nucleoside transporter; Hydrophobic nucleolar protein 36 kDa; Nucleoside transporter ei-type; Solute carrier family 29 member 2

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-181914
Research Areas:  

Cancer

UNC7242 is an antagonist that binds to the Tudor domains of PHF1 and PHF19, with a Kd of 1.13 μM for PHF1 and 0.64 μM for PHF19. UNC7242 fails to displace full-length PHF1 or PHF19 from H3K36me3 nucleosomes or chromatin. UNC7242 can be used in studies related to multiple myeloma, endometrial stromal sarcoma, and ossifying fibromyxoid tumor .
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