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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
CD147
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "CD147" in MCE Product Catalog:
6
6 Cited Publications
AC-73 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts CD147 dimerization, thereby mainly suppressing the CD147/ERK1/2/STAT3/MMP-2 pathways. AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells . AC-73 is also an anti-proliferative agent and an inducer of autophagy in leukemic cells .
Cat. No.: HY-P991501
Synonyms: HcHAb18
Cat. No.: HY-P991104
Target:
Research Areas:
Cat. No.: HY-RS01643
Target:
Research Areas:
BSG Human Pre-designed siRNA Set A contains three designed siRNAs for BSG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P83689A
Synonyms: HT-7; CD147; EMMPRIN; AI115436; AI325119; BSG; Basigin; 5F7; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD antigen CD147
Cat. No.: HY-P992115
CAS No.: 3055975-56-6
Cat. No.: HY-P991883
Synonyms: Licartin; Metuximab; Mehuzumab
Target:
Research Areas:
Cat. No.: HY-184926
Target:
LYTACs Asialoglycoprotein Receptor (ASGPR) Monocarboxylate Transporter Mitochondrial Metabolism MMP Cadherin
Research Areas:
PEG9MA10-PAB10-GalMA10 is a CD147 LYTAC degrader. PEG9MA10-PAB10-GalMA10 binds to the asialoglycoprotein receptor (ASGPR) via its galactose methacrylate domain, mediating its uptake by hepatoma cells. PEG9MA10-PAB10-GalMA10 induces lysosome-dependent degradation of CD147, resulting in concurrent loss of associated MCT1 and MCT4. PEG9MA10-PAB10-GalMA10 reduces extracellular lactate levels, increases intracellular lactate accumulation, inhibits glycolytic activity, and enhances mitochondrial respiratory capacity. PEG9MA10-PAB10-GalMA10 decreases the secretion of MMP-2 and MMP-9, and upregulates the expression of E-cadherin. PEG9MA10-PAB10-GalMA10 exhibits anti-tumor efficacy in hepatoma models. PEG9MA10-PAB10-GalMA10 can be used for research on liver cancer (hepatocellular carcinoma) .
Cat. No.: HY-RS17393
Target:
Research Areas:
Bsg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bsg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72350
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BSG; Leukocyte Activation Antigen M6; Prev. OK; Hepatoma-Associated Antigen; EMMPRIN; OK Blood Group Antigen; Basigin; HAb18G; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; Extracellular Matrix Metalloproteinase Inducer; 5F7; EMPRIN; Ok Blood G
Species:
Human
Source:
HEK293
Cat. No.: HY-P701289
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BSG; Leukocyte Activation Antigen M6; Prev. OK; Hepatoma-Associated Antigen; EMMPRIN; OK Blood Group Antigen; Basigin; HAb18G; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; Extracellular Matrix Metalloproteinase Inducer; 5F7; EMPRIN; Ok Blood G
Species:
Human
Source:
HEK293
Cat. No.: HY-P70029
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BSG; Leukocyte Activation Antigen M6; Prev. OK; Hepatoma-Associated Antigen; EMMPRIN; OK Blood Group Antigen; Basigin; HAb18G; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; Extracellular Matrix Metalloproteinase Inducer; 5F7; EMPRIN; Ok Blood G
Species:
Human
Source:
HEK293
Cat. No.: HY-P703747
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Species:
Canine
Source:
HEK293
Cat. No.: HY-P75481
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BSG; Leukocyte Activation Antigen M6; Prev. OK; Hepatoma-Associated Antigen; EMMPRIN; OK Blood Group Antigen; Basigin; HAb18G; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; Extracellular Matrix Metalloproteinase Inducer; 5F7; EMPRIN; Ok Blood G
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75480
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BSG; Leukocyte Activation Antigen M6; Prev. OK; Hepatoma-Associated Antigen; EMMPRIN; OK Blood Group Antigen; Basigin; HAb18G; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; Extracellular Matrix Metalloproteinase Inducer; 5F7; EMPRIN; Ok Blood G
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
