CD147

By Targets:	ADC Antibody (1) Apoptosis (1) Autophagy (1) Bcl-2 Family (1) Caspase (1) CDK (1) Integrin (2) SARS-CoV (1) Small Interfering RNA (siRNA) (2) Transmembrane Glycoprotein (1)
By Research Areas:	Cancer (4) Infection (1) Metabolic Disease (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Targets Recommended: CD1 CD38 CD28 CD19 CD20 CD22 Transferrin Receptor CD3 P-selectin CD6 CD2 CD276/B7-H3 CD73 c-Kit LAG-3 L-Selectin CTLA-4 CD47 ALCAM/CD166 Neprilysin E-Selectin Scavenger Receptor Class B type I (SR-BI） FLT3 Tim3 CD44 Anaplastic lymphoma kinase (ALK) CD74 Human leukocyte immunoglobulin (Ig)-like receptors (LILR) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-122214

AC-73 5+ Cited Publications	Autophagy	Cancer
AC-73 is a first specific, orally active inhibitor of cluster of differentiation 147 (CD147), which specifically disrupts *CD147* dimerization, thereby mainly suppressing the *CD147*/ERK1/2/STAT3/MMP-2 pathways. AC-73 inhibits the motility and invasion of hepatocellular carcinoma cells . AC-73 is also an anti-proliferative agent and an inducer of autophagy in leukemic cells .

HY-P991501

Meplazumab HcHAb18	ADC Antibody Transmembrane Glycoprotein SARS-CoV	Infection Cancer
Meplazumab (HcHAb18) is a humanized anti-CD147 IgG1 antibody a K_d of 0.47 nM. Meplazumab shows anti-SARS-CoV-2 and antitumor activity. Meplazumab conjugated with DM1 can form an antibody-conjugated drug ( HcHAb18-DM1), which induces G2/M phase cell cycle arrest and exerts antiproliferative activity in cancer cells. Meplazumab can be used for the researches of COVID-19 pneumonia and non-small cell lung cancer .

HY-P991104

*Anti-EMMPRIN/CD147* Antibody**	Integrin	Metabolic Disease
Anti-EMMPRIN/CD147 Antibody is a human antibody expressed in CHO cells, targeting Basigin. Anti-EMMPRIN/CD147 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-RS01643

BSG Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BSG Human Pre-designed siRNA Set A contains three designed siRNAs for BSG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BSG Human Pre-designed siRNA Set A BSG Human Pre-designed siRNA Set A

HY-P992115

Furtisetabart	Integrin	Cancer
Furtisetabart is a humanized monoclonal antibody targeting *CD147* with anti-tumor activity. Furtisetabart is of the human IgG4κ antibody subtype, and the recommended isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P991883

Metuzumab Licartin; Metuximab; Mehuzumab	Apoptosis CDK Caspase Bcl-2 Family	Cancer
Metuzumab (Licartin) is a human-mouse chimeric IgG1 monoclonal antibody targeting CD147. Metuzumab induces Apoptosis, reduces levels of Cyclin D1, full-length Caspase-3, and Bcl-2, and increases Bax expression. Metuzumab enhances the sensitivity of non-small cell lung cancer (NSCLC) cells to Gemcitabine (HY-17026). Metuzumab is applicable for research on hepatocellular carcinoma and non-small cell lung cancer [1] [2]_.

HY-RS17393

Bsg Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bsg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bsg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bsg Mouse Pre-designed siRNA Set A Bsg Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area	Image

HY-P991501

Meplazumab HcHAb18	ADC Antibody Transmembrane Glycoprotein SARS-CoV	Infection Cancer
Meplazumab (HcHAb18) is a humanized anti-CD147 IgG1 antibody a K_d of 0.47 nM. Meplazumab shows anti-SARS-CoV-2 and antitumor activity. Meplazumab conjugated with DM1 can form an antibody-conjugated drug ( HcHAb18-DM1), which induces G2/M phase cell cycle arrest and exerts antiproliferative activity in cancer cells. Meplazumab can be used for the researches of COVID-19 pneumonia and non-small cell lung cancer .

HY-P991104

*Anti-EMMPRIN/CD147* Antibody**	Integrin	Metabolic Disease
Anti-EMMPRIN/CD147 Antibody is a human antibody expressed in CHO cells, targeting Basigin. Anti-EMMPRIN/CD147 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992115

Furtisetabart	Integrin	Cancer
Furtisetabart is a humanized monoclonal antibody targeting *CD147* with anti-tumor activity. Furtisetabart is of the human IgG4κ antibody subtype, and the recommended isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .

HY-P991883

Metuzumab Licartin; Metuximab; Mehuzumab	Apoptosis CDK Caspase Bcl-2 Family	Cancer
Metuzumab (Licartin) is a human-mouse chimeric IgG1 monoclonal antibody targeting CD147. Metuzumab induces Apoptosis, reduces levels of Cyclin D1, full-length Caspase-3, and Bcl-2, and increases Bax expression. Metuzumab enhances the sensitivity of non-small cell lung cancer (NSCLC) cells to Gemcitabine (HY-17026). Metuzumab is applicable for research on hepatocellular carcinoma and non-small cell lung cancer [1] [2]_.

Recombinant Proteins Recommended:

CD147

Species:	Human (6) Mouse (3) Cynomolgus (1) Canine (1)
Tag:	His (9) Tag Free (1) Avi (1) Fc (2)
Source:	HEK293 (11)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72751

	*Basigin/CD147* Protein, Mouse (304a.a, HEK293, His)** Basigin; HT7 antigen; CD147; Bsg; EMMPRIN	Mouse	HEK293
	The Basigin/CD147 protein is essential for retinal maturation and development, acting as a NXNL1 receptor to promote the survival of retinal cone photoreceptor cells. Basigin/CD147 Protein, Mouse (304a.a, HEK293, His) is the recombinant mouse-derived Basigin/CD147 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P701289

	*FITC-Labeled Basigin/CD147* Protein, Human (HEK293, His)** Basigin; BSG; 5F7; CD147; EMMPRIN; M6; OK; TCSF	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. FITC-Labeled Basigin/CD147 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled Basigin/CD147 protein, expressed by HEK293 , with His labeled tag.

HY-P70029

	*Basigin/CD147* Protein, Human (HEK293, His)** rHuBasigin/CD147, His ; Basigin; 5F7; Collagenase Stimulatory Factor; Extracellular Matrix Metalloproteinase Inducer; EMMPRIN; Leukocyte Activation Antigen M6; OK Blood Group Antigen; Tumor Cell-Derived Collagenase Stimulatory Factor; TCSF; CD147; BSG	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (HEK293, His) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72350

	*Basigin/CD147* Protein, Human (Biotinylated, HEK293, Avi-His)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P74388

	*Basigin/CD147* Protein, Human (HEK293)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (HEK293) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with tag free.

HY-P75481

	*Basigin/CD147* Protein, Mouse (HEK293, His)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Mouse	HEK293
	The Basigin/CD147 protein is essential for retinal maturation and development, acting as a NXNL1 receptor to promote the survival of retinal cone photoreceptor cells. Basigin/CD147 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Basigin/CD147 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76202

	*Basigin/CD147* Protein, Cynomolgus (HEK293, His)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Cynomolgus	HEK293
	Basigin, also called CD147 or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily with homology to both the immunoglobulin V domain and major histocompatibility complex class II antigen 尾-chain. Basigin is the receptor for cyclophilins, S100A9 and platelet glycoprotein VI. Basigin tightly associates with monocarboxylate transporters and is essential for their cell surface translocation and activities . Basigin/CD147 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Basigin/CD147 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75480

	*Basigin/CD147* Protein, Mouse (HEK293, His-Fc)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Mouse	HEK293
	The Basigin/CD147 protein is essential for retinal maturation and development, acting as a NXNL1 receptor to promote the survival of retinal cone photoreceptor cells. Basigin/CD147 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived Basigin/CD147 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.

HY-P74387

	*Basigin/CD147* Protein, Human (HEK293, Fc)** Basigin; HT7 antigen; Membrane glycoprotein gp42; Bsg	Human	HEK293
	Basigin/BSG proteins are critical for retinal maturation and development and function as retinal cell receptors for NXNL1, promoting the survival of retinal cone photoreceptors. Basigin/CD147 Protein, Human (HEK293, Fc) is the recombinant human-derived Basigin/CD147 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P703693

	*EMMPRIN/CD147* Protein, Human (HEK293, His)**	Human	HEK293
	EMMPRIN/CD147 Protein, Human (HEK293, His) is the recombinant human-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.

HY-P703747

	*EMMPRIN/CD147* Protein, Canine (HEK293, His)**	Canine	HEK293
	EMMPRIN/CD147 Protein, Canine (HEK293, His) is the recombinant canine-derived EMMPRIN/CD147 protein, expressed by HEK293, with C-His tag.

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Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
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Appearance
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Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (4) Mouse (1)
Application:	IHC-P (5) ICC/IF (4) IP (1) IHC-F (2) WB (3) FC (3) ELISA (2)
Isotype:	IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (5) Biotin (1)
Clonality:	Polyclonal (1) Monoclonal (2) Recombinant (1)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80596

	CD147 Antibody HT-7; CD147; EMMPRIN; AI115436; AI325119	WB, IHC-P, FC, IP	Mouse
	CD147 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CD147.

HY-P83689

	CD147 Antibody (YA3422) HT-7; CD147; EMMPRIN; AI115436; AI325119; BSG; Basigin; 5F7; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD antigen CD147	WB, IHC-P, IHC-F, ICC/IF	Human
	CD147 Antibody (YA3422) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD147.

HY-P83689A

	CD147 Antibody (YA3422)(PBS only) HT-7; CD147; EMMPRIN; AI115436; AI325119; BSG; Basigin; 5F7; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD antigen CD147	WB, IHC-P, IHC-F, ICC/IF	Human
	CD147 Antibody (YA3422) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD147.

HY-P84277

	CD147 Antibody (YA3974) BSG; OK; 5F7; TCSF; EMMPRIN	IHC-P, ICC/IF, FC, ELISA	Human
	CD147 Antibody (YA3974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD147.

HY-P84277A

	CD147 Antibody (YA3974)(PBS only) BSG; OK; 5F7; TCSF; EMMPRIN	IHC-P, ICC/IF, FC, ELISA	Human
	CD147 Antibody (YA3974) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD147.

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Products	In-stock - + Add to Cart
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Host
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS01643

BSG Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BSG Human Pre-designed siRNA Set A contains three designed siRNAs for BSG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS17393

Bsg Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Bsg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bsg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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