40 Results for "

CEACAM5

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "CEACAM5" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
2
2 Cited Publications
Cat. No.: HY-P70675
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e; CEACAM5
Species:  
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1
1 Cited Publications
Cat. No.: HY-P99542
CAS No.: 2254086-60-5
Synonyms: SAR-408701; HuMAb2-3-SPDB-DM4
Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5, composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8 .
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Cat. No.: HY-P99054
CAS No.: 2349294-95-5
Synonyms: SAR-408377; PF-08046050 Antibody; SAR445953 Antibody

Research Areas:  

Cancer

Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize ADC Tusamitamab ravtansine (SAR408701) (HY-P99542) .
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Cat. No.: HY-177434
CAS No.: 2873366-83-5
Synonyms: Precem-TcT; M 9140
Precemtabart tocentecan (Precem-TcT; M 9140) is an anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody-drug conjugate (ADC). Precemtabart tocentecan consists of a tumor-specific anti-CEACAM5 monoclonal antibody Precemtabart (HY-P990940), a highly hydrophilic and stable cleavable β-glucuronide linker, and a topoisomerase 1 inhibitor payload Exatecan (HY-13631), and the drug-linker conjugate for ADC is Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179). Precemtabart tocentecan inhibits the growth of CEACAM5-positive cancer cells. Precemtabart tocentecan exhibits significant antitumor activity in CEACAM5-expressing xenograft models. Precemtabart tocentecan can be used for the study of CEACAM5-expressing advanced solid tumors, especially mCRC .
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Cat. No.: HY-P99681
CAS No.: 1469876-18-3
Synonyms: IMMU 130; hMN-14-SN-38
Research Areas:  

Cancer

Labetuzumab govitecan (IMMU 130) is an Anti-CEACAM5/SN-38 antibody-drug conjugate (ADC). Labetuzumab govitecan consists of the antibody Labetuzumab, SN-38, and a pH-sensitive Linker. Labetuzumab govitecan can be used for research of cancers, such as colorectal cancer .
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Cat. No.: HY-164899
CAS No.: 2765091-45-8
Synonyms: 2-aminopyridine-3-carboxylic acid imidazolide
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

2A3 (2-aminopyridine-3-carboxylic acid imidazolide) is a covalent probe reagent for Selective 2'-Hydroxyl Acylation analyzed by Primer Extension (SHAPE) that targets the RNA ribose 2'-OH group. 2A3 efficiently permeates the biological membranes of Gram-negative bacteria, Gram-positive bacteria, and mammalian cells. 2A3 exhibits no base bias and specifically labels conformationally flexible, unpaired regions within RNA. 2A3 forms covalent adducts by acylating the 2'-OH groups of flexible RNA residues. When combined with SHAPE-MaP (mutational profiling) sequencing technology, these modification sites are converted into detectable mutational signals, thereby accurately reflecting local RNA backbone flexibility and base-pairing status. 2A3 is primarily utilized in molecular biology and transcriptomics research, including the resolution of RNA structuromes in living cells, the study of RNA folding regulatory mechanisms, and the investigation of non-coding RNA functions .
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Cat. No.: HY-P990940
CAS No.: 2883118-92-9
Synonyms: MBE-748; M-9140 Antibody; MBE-2882 Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990940 is an CEACAM5-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991060
CAS No.: 1622305-37-6

Research Areas:  

Cancer

Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498) .
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Cat. No.: HY-RS02441
Research Areas:  

Others

CEACAM5 Human Pre-designed siRNA Set A contains three designed siRNAs for CEACAM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991469
Synonyms: MEDI-565

Research Areas:  

Cancer

AMG-211 (MEDI-565)i s a bispecific antibody targeting CD3E and CEACAM5/CEA/CD66e. AMG-211 can be used in Gastrointestinal cancer and Solid tumours research .
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Cat. No.: HY-P991563

Target:  

Inhibitory Antibodies

Research Areas:  

Others

Anti-CEACAM5 Antibody (A5B7) is a humanized antibody expressed in CHO cells, targeting CEACAM5/CEA/CD66e. Anti-CEACAM5 Antibody (A5B7) consists of a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for the Anti-CEACAM5 Antibody (A5B7) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990853

Research Areas:  

Cancer

Anti-CEACAM5 Antibody (4H11-8) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM5. Anti-CEACAM5 Antibody (4H11-8) reacts with human CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5). Anti-CEACAM5 Antibody (4H11-8) can be used for detecting CEACAM5 in cancer.
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Cat. No.: HY-RS17043
Research Areas:  

Others

Ceacam5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ceacam5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990365

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

The Anti-CEACAM5/CEA/CD66e Antibody is a humanized antibody expressed in CHO cells, targeting CEACAM5/CEA/CD66e. The Anti-CEACAM5/CEA/CD66e Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for the Anti-CEACAM5/CEA/CD66e Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991936

Research Areas:  

Cancer

Anti-CEACAM5/CEA/CD66e Antibody (16C3) is an antibody against human CEACAM5/CEA/CD66e. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P78755
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM-5; CD66e; CEA; Meconium antigen 100
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Cat. No.: HY-P992350

Research Areas:  

Cancer

EBC-129 Antibody is a specific antibody for the synthetic antibody-drug conjugate (ADC) EBC-129, which specifically targets CEACAM5 and CEACAM6 glycosylated at N256. EBC-129 Antibody can be used for the research of pancreatic ductal adenocarcinoma .
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Cat. No.: HY-P78756
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM-5; CD66e; CEA; Meconium antigen 100
Species:  
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Cat. No.: HY-P992090
CAS No.: 156586-92-4
Altumomab is a anti-huamn monoclonal antibody targeting CEACAM5/CEA/CD66e .
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Cat. No.: HY-P72693
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; CEACAM5
Species:  
Source:  
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