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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
CLC
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "CLC" in MCE Product Catalog:
Synonyms: PROTAC Linker 4
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Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) .
Synonyms: NMD670
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NMD670 is an orally active inhibitor of skeletal muscle specific chloride channel ClC-1 with an EC50 of 1.6 μM. NMD670 enhances neuromuscular transmission and improves muscle contraction and strength. NMD670 can be used in the study of muscle weakness and muscle fatigue .
Cat. No.: HY-P1105
CAS No.: 194665-85-5
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Cat. No.: HY-P2040
CAS No.: 118399-22-7
Cat. No.: HY-W414069
CAS No.: 1249-81-6
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OADS is a Chloride channel antiporter (ClC-ec1) inhibitor (IC50: 29 μM). OADS specifically inhibits the ClC-ec1 antiporter but not the ClC-1 channel. OADS can be used for research of osteoporosis and neurodegenerative and cardiovascular diseases .
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Cl-C6-PEG4-C3-COOH is a PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs) .
Cat. No.: HY-RS02747
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CLC Human Pre-designed siRNA Set A contains three designed siRNAs for CLC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18058
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Clcf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clcf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Unoprostone, a prostaglandin F2α analog, is a large conductance Ca 2+-activated K + (BK) channels and ClC-2 type chloride channels activator. Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and can be used for the study of glaucoma, ocular hypertension and retinitis pigmentosa .
Cat. No.: HY-43193
CAS No.: 1835705-78-6
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Cl-C6-PEG3-C3-acid is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-RS02752
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CLCF1 Human Pre-designed siRNA Set A contains three designed siRNAs for CLCF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-186078
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SRA-36 is a CLC-K chloride channel inhibitor with selectivity over CLC-5 and CLC-1 chloride channels. SRA-36 blocks CLC-Ka currents with an IC50 of 6.6 μM and a Kd of 3.8 μM. SRA-36 blocks chloride currents mediated by targeted channels, and inhibits currents from hypertension-associated CLC-Ka A447T and CLC-Ka Y315F polymorphisms. SRA-36 can be used for the research of hypertension .
Cat. No.: HY-182571
CAS No.: 15437-29-3
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AK-42 is a selective CLC-2 chloride channel inhibitor with human IC50 of 17 nM and rat IC50 of 14 nM. AK-42 binds to an extracellular vestibule above the channel pore, inhibits CLC-2 currents acutely and reversibly, including with auxiliary subunit GlialCAM coexpression. AK-42 acts as a selective tool compound for acute CLC-2 function modulation to probe CLC-2 neurophysiology. AK-42 can be used for the research of leukodystrophy and idiopathic generalized epilepsies .
Cat. No.: HY-RS24533
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Clcf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Clcf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-183088
CAS No.: 3024055-48-6
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Cl-C6-PEG8-NH2 (Compound Int-8) hydrochloride is a self-labeling protein reagent that can be used to synthesize photocatalysts .
Cat. No.: HY-P703106
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLCN1; Chloride Channel Protein 1; Chloride Voltage-Gated Channel 1; Chloride Channel, Voltage-Sensitive 1; CLC-1; Chloride Channel 1, Skeletal Muscle; CLC1; Thomsen Disease, Autosomal Dominant; Chloride Channel Protein, Skeletal Muscle; Uncharacterized P
Species:
Human
Source:
HEK293
Cat. No.: HY-P83424A
Synonyms: Charcot-Leyden crystal protein 2; CLC2; Galectin-14; Gal-14
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
