1 Result for "

CSC6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CSC6" in MCE Product Catalog:

Art. -Nr.: HY-161072
CAS. Nr.: 354559-44-7
Forschungsgebiete:  

Inflammation/Immunology

CSC-6 is a NLRP3 inhibitor. CSC-6 can significantly inhibit IL-1β secreted by PMATHP-1 cells with an IC50 value of 2.3 μM. CSC-6 specifically binds NLRP3 and inhibits NLRP3 activation by blocking ASC oligomerization during NLRP3 assembly. CSC-6 effectively reduces the symptoms of NLRP3 overactivation-mediated sepsis and gout in mouse models .
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