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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
CTR
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "CTR" in MCE Product Catalog:
5
5 Cited Publications
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MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC50 of 0.12 nM and Ki of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.
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3 Cited Publications
Cat. No.: HY-P3462
CAS No.: 1415456-99-3
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3
3 Cited Publications
Cat. No.: HY-P3462A
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1
1 Cited Publications
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ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite. ABMA selectively acts at host cell late endosomes rather than targeting toxin or pathogen itself. ABMA has broad-spectrum anti-infection activity .
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1 Cited Publications
Cat. No.: HY-P72011
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; CTR1; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 copper tansporters; member 1; Solute carrier family 31 member 1
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Cat. No.: HY-P10798
CAS No.: 2883634-40-8
Synonyms: LY-3841136
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Cat. No.: HY-P10798A
Synonyms: LY-3841136 sodium
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Cat. No.: HY-179738
CAS No.: 3097482-67-9
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CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator. CTR/AMYR modulator-1 can be used for the research of metabolic disease .
Cat. No.: HY-160267
CAS No.: 950403-60-8
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iPAF1C is a inhibitor of the polymerase-associated factor 1 complex (PAF1C) with specific targeting to the PAF1 binding groove of CTR9 (a key subunit of PAF1C). iPAF1C disrupts PAF1C assembly by interfering with the PAF1-CTR9 interaction. iPAF1C selectively impairs BRD4-mediated recruitment of PAF1 to chromatin at hypoxia-responsive genes and inhibits RNA polymerase II (RNAPII) pause release. iPAF1C increases the population of HIV-1 NL4.3 Nef-IRES-GFP infected primary human CD4 +T cells in a dose-dependent manner. PAF1C can be used for the study of infection and diseases associated with abnormal hypoxic adaptation (e.g., cancers, neurological disorders) .
Cat. No.: HY-P4863
CAS No.: 1678415-18-3
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Cat. No.: HY-RS03316
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CTR9 Human Pre-designed siRNA Set A contains three designed siRNAs for CTR9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22131
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Ctr9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ctr9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-185229
CAS No.: 3108097-26-0
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CTR/AMYR agonist-1 is a CTR/AMYR agonist with EC50 values of 0.56-6.9 nM. CTR/AMYR agonist-1 can be used for the research of metabolic disease .
Cat. No.: HY-RS01832
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CALCR Human Pre-designed siRNA Set A contains three designed siRNAs for CALCR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-185234
CAS No.: 3068779-36-9
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Cardiovascular Disease Neurological Disease Metabolic Disease
CTR/AMYR activator-1 (S configuration of compound 122) is a CTR/AMYR activator. CTR/AMYR activator-1 can be used in the research of bone diseases, metabolic diseases, cardiovascular diseases, and neurodegenerative diseases .
Cat. No.: HY-RS01833
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Calcr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Calcr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-185229A
CAS No.: 3108097-24-8
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CTR/AMYR agonist-1 enantiomer is an enantiomer of CTR/AMYR agonist-1 (HY-185229). CTR/AMYR agonist-1 is a CTR/AMYR agonist with EC50 values of 0.56-6.9 nM. CTR/AMYR agonist-1 can be used for the research of metabolic disease .
Cat. No.: HY-185234A
CAS No.: 3068778-30-0
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Cardiovascular Disease Neurological Disease Metabolic Disease
(R)-CTR/AMYR activator-1 (Compound 122) is a CTR/AMYR activator with EC50 values of 0.8 and 0.73 nM. (R)-CTR/AMYR activator-1 can used for the researches of bone diseases, metabolic diseases, cardiovascular diseases, and neurodegenerative diseases .
Cat. No.: HY-185107
CAS No.: 3108095-52-6
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CTR/AMYR modulator-2 (Example 107) is a receptor 3 for pancreatic amyloid peptide (bAMY3R) agonist, and its EC50 for stimulating cAMP production in cells is ＜500 nM. CTR/AMYR modulator-2 is also a receptor for calcitonin (bCTR) agonist, with its EC50 being ＜5000 nM. CTR/AMYR modulator-2 can be used for research on type 2 diabetes and obesity .
Cat. No.: HY-186104
CAS No.: 3097592-82-7
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AMYR/CTR agonist 1 is an amylin receptor (AMYR) and calcitonin receptor (CTR) agonist with an amylin receptor cAMP stimulation EC50 of 0.0995 nM and a calcitonin receptor cAMP stimulation EC50 of 0.00616 nM. AMYR/CTR agonist 1 can be used for the research of non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, insulin dependent diabetes, non-insulin dependent diabetes, impaired glucose tolerance, obesity, syndrome x .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
