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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
Ca2+ ATPase
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "Ca2+ ATPase" in MCE Product Catalog:
153
153 Publications Verification
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Infection Terpenoids Diterpenoids Plants Umbelliferae Disease Research Fields Cancer Thapsia garganica L.
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18 Cited Publications
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CDN1163 is an allosteric sarco/endoplasmic reticulum Ca 2+-ATPase (SERCA) activator that improves Ca 2+ homeostasis. CDN1163 attenuates diabetes and metabolic disorders .
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11 Cited Publications
Synonyms: (-)-Xestospongin C
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11
11 Cited Publications
Cat. No.: HY-N6778
CAS No.: 57186-25-1
5
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Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively . Also in anti-cancer research . Calmidazolium binds to calmodulin with a Kd of 3 nM.
4
4 Cited Publications
Synonyms: (S)-(+)-Abscisic acid; ABA
3
3 Cited Publications
Synonyms: N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine
BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC50s of ~5 µM for actin- and Ca 2+-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers .
2
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Cardiovascular Disease Plants Brassicaceae Disease Research Fields Erysimum cheiranthoides Linn. Steroids
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2
2 Cited Publications
Cat. No.: HY-P3278
CAS No.: 350670-85-8
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2
2 Cited Publications
Cat. No.: HY-P3278A
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1
1 Cited Publications
Cat. No.: HY-W019981B
CAS No.: 7791-18-6
Synonyms: MgCl2 hexahydrate, for molecular biology
1
1 Cited Publications
Cat. No.: HY-W019981C
CAS No.: 7791-18-6
Synonyms: MgCl2 hexahydrate, for cell culture
1
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Benzocaine is an orally active local anesthetic. Benzocaine non-competitively inhibits the binding of Ca-ATPase to Ca 2+, with an IC50 of 47.1 mM. Benzocaine exerts anesthetic effects by blocking voltage-gated sodium channels. Benzocaine induces methemoglobinemia in various experimental animals .
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1
1 Cited Publications
Cat. No.: HY-Y0258A
CAS No.: 23239-88-5
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Benzocaine hydrochloride is an orally active local anesthetic. Benzocaine hydrochloride non-competitively inhibits the binding of Ca-ATPase to Ca 2+, with an IC50 of 47.1 mM. Benzocaine hydrochloride exerts anesthetic effects by blocking voltage-gated sodium channels. Benzocaine hydrochloride induces methemoglobinemia in various experimental animals .
1
1 Cited Publications
Cat. No.: HY-135110
CAS No.: 208445-06-1
Synonyms: Rp-8-bromo-Cyclic GMPS sodium
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Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca 2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca 2+ reduction by activating Ca 2+-ATPase and subsequently removing Ca 2+ from the cell .
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Biacetyl monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor. Biacetyl monoxime is also a well-characterized non-competitive inhibitor of chemical and motile activity of skeletal muscle myosin-II. Biacetyl monoxime induces sarcoplasmic reticulum Ca 2+ release .
Cat. No.: HY-P3617
CAS No.: 32204-93-6
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Cat. No.: HY-W012399
CAS No.: 88-58-4
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2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA) inhibitor with an IC50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca 2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 (IC50: 1.8 and 14.1 μM for 5-LO and COX-2, respectively) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
