41 Results for "

Cardiac glycoside

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "Cardiac glycoside" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-N1441
CAS No.: 482-39-3
Synonyms: Kaempferol-3-O-rhamnoside
Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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7
7 Cited Publications
Cat. No.: HY-B1030
CAS No.: 17575-22-3
Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71 .
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2
2 Cited Publications
Cat. No.: HY-114252
CAS No.: 66-28-4
Purity:  93.31%
Strophanthidin is a naturally available cardiac glycoside . Strophanthidin 0.1 and 1 nmol/L increases and 1~100 μmol/L inhibits the Na+/K+-ATPase activities, but Strophanthidin 10 and 100 nmol/L does not affect Na+/K+-ATPase activities in cardiac sarcolemmal . Strophanthidin increases both diastolic and systolic intracellular Ca 2+ concentration .
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1
1 Cited Publications
Cat. No.: HY-N2414
CAS No.: 514-39-6
Periplogenin is an orally active cardiac glycoside found in Cortex periplocae. Periplogenin can induce ROS production and necroptosis and cause G0/G1 phase arrest. Periplogenin can inhibit pyroptosis by regulating the NLRP3/Caspase-1/GSDMD signaling. Periplogenin suppresses growth of prostate carcinoma cells by docking to an ATP1A1 protein pocket and forming a hydrogen bond with T804. Periplogenin can be used for the researches of cancer, inflammation and immunology, such as prostate carcinoma, rheumatoid arthritis and psoriasis .
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1
1 Cited Publications
Cat. No.: HY-N2453
CAS No.: 508-75-8
Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved in its transport. Convallatoxin is an enhancer of ligand-induced MOR endocytosis with high potency and efficacy. Anti-inflammatory and anti-proliferative properties .
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1
1 Cited Publications
Cat. No.: HY-N4252
CAS No.: 32476-67-8
Periplocymarin, a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound .
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1
1 Cited Publications
Cat. No.: HY-16022
CAS No.: 1111-39-3
Synonyms: Digitoxin 3'''-Acetate
Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch .
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Cat. No.: HY-A0154
CAS No.: 17598-65-1
Synonyms: Deacetyllanatoside C; Desacetyllanatoside C
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
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Cat. No.: HY-N8441
CAS No.: 466-07-9
Synonyms: 17β-Neriifolin
Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na +, K +-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells [2.
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Cat. No.: HY-111934
CAS No.: 508-77-0
Purity:  97.28%
Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K + release (IC50=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant .
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Cat. No.: HY-W779529
CAS No.: 25633-33-4
Synonyms: 2'-Acetylneriifolin
Target:  

Na+/K+ ATPase

Research Areas:  

Cancer

Cerberin is a cardiac glycoside that has been found in C. odollam and has cytotoxic and cardiac modulatory activities. It is cytotoxic to KB and NCI H187 cancer cells (IC50s=1.92 and 1.24 μg/mL).1 Cerberin inhibits Na+/K+-ATPase, increasing intracellular sodium levels and action potential duration in cardiac cells.
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Cat. No.: HY-W671746
CAS No.: 37933-66-7
Thevetin A is a thevetia cardiac glycoside. Thevetin A can be isolated from the methanol extract of the seeds of Cascabela thevetioides .
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Cat. No.: HY-N1156
CAS No.: 27127-79-3
Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana .
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Cat. No.: HY-N1441R
CAS No.: 482-39-3
Synonyms: Kaempferol-3-O-rhamnoside (Standard)
Afzelin (Standard) is the analytical standard of Afzelin. This product is intended for research and analytical applications. Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin .
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Cat. No.: HY-N11250
CAS No.: 124-99-2
Scillaren A is a cardiac glycoside, can be isolated from the bulbs of D. coromandeliana .
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Cat. No.: HY-N8735
CAS No.: 33279-57-1
k-Strophanthoside is a cardiac glycoside compound that can be isolated from the seeds of Strophanthus kombe .
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Cat. No.: HY-N9149
CAS No.: 98570-81-1
Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB .
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Cat. No.: HY-W741940
CAS No.: 508-93-0
Evomonoside is a type of cardiac glycoside compound. Evomonoside exhibits significant in vitro anticancer activity, especially having nanomolar inhibitory concentrations against gastric cancer cell lines. Evomonoside has typical cardiac toxicity risks, including arrhythmias and conduction abnormalities. Evomonoside can be used for research on gastric cancer .
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Cat. No.: HY-105431
CAS No.: 59006-00-7
Target:  

Na+/K+ ATPase

Research Areas:  

Cardiovascular Disease

ASI-222 is an aminosugar cardiac glycoside. ASI-222 can inhibit Na+/K+ ATPase and show positive inotropic effect. ASI-222 can be used for the research of cardiovascular disease .
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Cat. No.: HY-N12799
CAS No.: 752-61-4
Synonyms: Digitalinum verum
Digitalin (Digitalinum verum) is a cardiac glycoside and can be isolated from Digitalis .
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