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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Cortisone
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Cortisone" in MCE Product Catalog:
6
6 Cited Publications
Synonyms: 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E
3
Cat. No.: HY-17461S1
CAS No.: 1257650-98-8
Cat. No.: HY-18056
CAS No.: 857290-04-1
Target:
Research Areas:
PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively .
Synonyms: 17-Hydroxy-11-dehydrocorticosterone(Standard); Kendall's compound E (Standard)
Cat. No.: HY-W741510
CAS No.: 1882-82-2
Synonyms: 21-DesoxyCortisone; NSC 38722
Target:
Research Areas:
21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is formed from 11-ketoprogesterone by the cytochrome P450 (CYP) isozyme CYP17A1, but can also be produced by oxidation of 21-deoxycortisone (HY-113405) by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Congenital adrenal hyperplasia is an inborn error of metabolism characterized by a deficiency of 21-hydroxylase, and 21-Deoxy Cortisone levels are elevated in patients with congenital adrenal hyperplasia.
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Research Areas:
Flumethasone (Standard) is the analytical standard of Flumethasone. This product is intended for research and analytical applications. Flumethasone is a corticosteroid, a topical agent used in combination with Clioquinol for the study of otitis externa and otomycosis. When used in animal models, Flumethasone's anti-inflammatory activity is 420 times higher than that of Cortisone.
Cat. No.: HY-N8549A
CAS No.: 28423-48-5
Category:
Cardiacglycosides Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
Cat. No.: HY-17461S
CAS No.: 2350278-95-2
Cat. No.: HY-105286
CAS No.: 1114561-85-1
Target:
Research Areas:
BI-135585 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with an IC50 of 13 nM. BI-135585 exhibits >1000-fold selectivity over other hydroxysteroid dehydrogenases. BI-135585 can be used for type 2 diabetes research .
Cat. No.: HY-17461AR
CAS No.: 50-04-4
Synonyms: Cortisone 21-acetate (Standard)
Cat. No.: HY-141728
CAS No.: 789440-10-4
Synonyms: BCIPP
Target:
Cat. No.: HY-W742382
Cat. No.: HY-17461S3
CAS No.: 2687960-86-5
Synonyms: 17-Hydroxy-11-dehydrocorticosterone-d2; Kendall's compound E-d2
Cat. No.: HY-113114S
Cat. No.: HY-113114S1
Cat. No.: HY-113114R
CAS No.: 53-05-4
Category:
Cat. No.: HY-113114S2
CAS No.: 1485501-48-1
Cat. No.: HY-145381
CAS No.: 1303515-33-4
Target:
Research Areas:
11β-HSD1-IN-6 is a an 11β-HSD-1 inhibitor. The 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs) mediate the interconversion of the glucocorticoid (GC) corticosterone or cortisol to an inactive form, 11-dehydrocorticosterone (11-DHC) or Cortisone, respectively .
Cat. No.: HY-18056R
CAS No.: 857290-04-1
Target:
Research Areas:
PF-915275 (Standard) is the analytical standard of PF-915275. This product is intended for research and analytical applications. PF-915275 is a potent, selective and orally active human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor with a Ki of 2.3 nM and an EC50 of 15 nM (in HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
