19 Results for "

Cx43

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Cx43" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P1136
CAS No.: 1507930-57-5
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial .
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5
5 Cited Publications
Cat. No.: HY-P1136A
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19 TFA, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 TFA is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 TFA has protective effects against myocardial .
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5
5 Cited Publications
Cat. No.: HY-P0154
CAS No.: 182683-50-7
Synonyms: ε-V1-2; EAVSLKPT
Target:  

PKC

Research Areas:  

Inflammation/Immunology

Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC .
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2
2 Cited Publications
Cat. No.: HY-P1136B
CAS No.: 1507930-54-2
TAT-Gap19, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 traverses the blood-brain barrier and alleviate liver fibrosis in mice .
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2
2 Cited Publications
Cat. No.: HY-P1136C
TAT-Gap19 TFA, a Cx mimetic peptide, is a specific connexin43 hemichannel (Cx43 HC) inhibitor. TAT-Gap19 TFA does not inhibits the corresponding Cx43 GJCs. TAT-Gap19 TFA traverses the blood-brain barrier and alleviate liver fibrosis in mice .
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1
1 Cited Publications
Cat. No.: HY-106225
CAS No.: 355151-12-1
Purity:  99.50%
Synonyms: ZP123
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation .
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1
1 Cited Publications
Cat. No.: HY-P72205
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Connexin 43; Connexin-43; Cx 43; Cx43; CxA1_HUMAN; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; Gap junction protein alpha 1 43kDa connexin 43; ; Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; Gja1; GJAL; ODD; ODDD; ODOD; SDTY3
Species:  
Source:  
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Cat. No.: HY-P10849
CAS No.: 3061802-23-8
Target:  

Calcium Channel

Research Areas:  

Others

IP3RPEP6 is an IP3R competitive inhibitor. IP3RPEP6 has the IC50 values of 9.0 μM, 3.9 μM and 4.3 μM for IP3R1, IP3R2 and IP3R3, respectively. IP3RPEP6 does not affect the Ryanodine receptor and Cx43 hemichannels. IP3RPEP6 regulates calcium signaling within cells .
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Cat. No.: HY-167983
CAS No.: 1840896-10-7
Target:  

Gap Junction Protein

Research Areas:  

Neurological Disease

Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels (Cx43 HC). Cx43 HC-IN-1 effectively inhibits the hemichannel activity mediated by Cx43/Cx45 in denervated skeletal muscle fibers, significantly increasing the reinnervation rate of muscle fibers by neurons. Cx43 HC-IN-1 reduces neuroinflammation and neuronal overexcitation by inhibiting hemichannels in glial cells in the brain, and alleviates epilepsy in mice. Cx43 HC-IN-1 can be used for research on epilepsy and muscle diseases .
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Cat. No.: HY-P11197
CAS No.: 895547-36-1
Target:  

Gap Junction Protein

Research Areas:  

Cancer

ACT1 is a peptide that targets endogenous Cx43 by stabilizing its activity at gap junctions. ACT1 stabilizes gap junction intercellular communication in breast cancer cells. ACT1 enhances the activity of Tamoxifen (HY-13757A) and Lapatinib (HY-50898) in breast cancer. ACT1 can be used for breast cancer research .
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Cat. No.: HY-106225R
CAS No.: 355151-12-1
Synonyms: ZP123 (Standard)
Rotigaptide (Standard) is the analytical standard of Rotigaptide. This product is intended for research and analytical applications. Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically?atrial fibrillation .
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Cat. No.: HY-177644
CAS No.: 287122-58-1
Target:  

Connexin

Research Areas:  

Others

Lufepirsen is an unmodified antisense oligonucleotide targeted to Connexin43 (Cx43). Connexin43 is a specific protein in the eye, which plays a role in wound healing.
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Cat. No.: HY-177644A
Target:  

Connexin

Research Areas:  

Others

Lufepirsen sodium is an unmodified antisense oligonucleotide targeted to Connexin43 (Cx43). Connexin43 is a specific protein in the eye, which plays a role in wound healing.
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Cat. No.: HY-P992010

Target:  

Gap Junction Protein

Research Areas:  

Cancer

ALMB-0168 is a Cx43 hemichannel agonist monoclonal antibody. ALMB-0168 activates Cx43 hemichannels to inhibit the growth and migration of osteosarcoma. ALMB-0168 is applicable to relevant research on osteosarcoma .
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Cat. No.: HY-P86348
Synonyms: GJA1; GJAL; Gap junction alpha-1 protein; Connexin-43; Cx43; Gap junction 43 kDa heart protein

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS25249
Research Areas:  

Others

Gja1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gja1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS05440
Research Areas:  

Others

GJA1 Human Pre-designed siRNA Set A contains three designed siRNAs for GJA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P80628
Synonyms: Connexin 43; Connexin-43; Cx 43; Cx43; CxA1_HUMAN; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; Gap junction protein alpha 1 43kDa (connexin 43); Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; Gja1;

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-RS18762
Research Areas:  

Others

Gja1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gja1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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