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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
CypD
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "CypD" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N1511
CAS No.: 108340-60-9
1
1 Cited Publications
Cat. No.: HY-P71224
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase D; PPIase D; 40 kDa Peptidyl-Prolyl Cis-Trans Isomerase; Cyclophilin-40; CYP-40; Cyclophilin-Related Protein; Rotamase D; PPID; CYP40; CypD
Cat. No.: HY-157088
Purity: 99.49%
Target:
Research Areas:
C105SR is a cyclophilin D (CypD) inhibitor targeting to peptidyl-prolylcis-trans isomerase (PPIase). C105SR inhibits mitochondrial permeability transition opening (mPTP) with an IC 50 of 5 nM. C105SR inhibits hypoxia and reoxygenation inudced hepatocyte apoptosis and increases the level of calcium retention capacity (CRC). C105SR exhibits hepaprotective effect in ischaemia-reperfusion injury (IRI) mouse model .
Cat. No.: HY-151487
CAS No.: 2651994-75-9
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CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes .
Cat. No.: HY-151488
CAS No.: 3023438-19-6
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Research Areas:
CypD-IN-4 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-4 has CypD affinity with an IC50 value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes .
Cat. No.: HY-116095
CAS No.: 1572646-93-5
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CypD-IN-5 (compound C-9) is a potent cyclophilin D (CypD) inhibitor. CypD-IN-5 can be used in the study of Alzheimer's disease .
Cat. No.: HY-136804
CAS No.: 1115335-95-9
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Research Areas:
CypD-IN-29 (compound 29) is an inhibitor of the Alzheimer's disease target CypD (KD=88.2 nM). CypD is a mitochondrial-specific cyclophilin that can bind to β-amyloid protein in brain mitochondria and promote the formation of mitochondrial permeability transition pore (mPTP).
Cat. No.: HY-179416
Target:
Research Areas:
CypD-IN-6 is a potent cyclophilin D (CypD/PPIF) inhibitor that inhibits CypD PPIase activity (Ki = 32 nM) and binds to CypD (Kd = 60 nM). CypD-IN-6 can be used for mitochondrial permeability transition pore (MPTP) related disease research such as ischemia-reperfusion injury and acute pancreatitis 1.
Cat. No.: HY-179417
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Research Areas:
CypD-IN-7 is a potent cyclophilin D (CypD/PPIF) inhibitor that inhibits CypD PPIase activity (K i = 2.4 nM) and provides protection against mitochondrial permeability transition pore (MPTP) opening. CypD-IN-7 can be used for pancreatitis research .
Cat. No.: HY-N1511R
CAS No.: 108340-60-9
Target:
Cat. No.: HY-RS10951
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Research Areas:
PPIF Human Pre-designed siRNA Set A contains three designed siRNAs for PPIF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10949
Target:
Research Areas:
PPID Human Pre-designed siRNA Set A contains three designed siRNAs for PPID gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25864
Target:
Research Areas:
Ppid Rat Pre-designed siRNA Set A contains three designed siRNAs for Ppid gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11489
CAS No.: 252731-57-0
Research Areas:
Cat. No.: HY-P71224A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase D; PPIase D; 40 kDa Peptidyl-Prolyl Cis-Trans Isomerase; Cyclophilin-40; CYP-40; Cyclophilin-Related Protein; Rotamase D; PPID; CYP40; CypD
Cat. No.: HY-RS25273
Target:
Research Areas:
Ppif Rat Pre-designed siRNA Set A contains three designed siRNAs for Ppif gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18784
Target:
Research Areas:
Ppif Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ppif gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
