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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
DED
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "DED" in MCE Product Catalog:
Cat. No.: HY-P10904
CAS No.: 51486-77-2
Synonyms: ST-100
Cat. No.: HY-W143531
CAS No.: 133331-77-8
Synonyms: NOV03; SHR8058
Target:
Research Areas:
Perfluorohexyloctane (NOV03), a semifluorinated alkane, reduces tear film instability in Meibomian gland dysfunction and evaporative dry eye disease. Perfluorohexyloctane is a long-term tamponade agent. Perfluorohexyloctane increases tear film breakup time and lipid layer thickness .
Synonyms: SYL1001
Research Areas:
Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA .
Cat. No.: HY-RS00034
Target:
Research Areas:
AATF Human Pre-designed siRNA Set A contains three designed siRNAs for AATF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-154994
CAS No.: 2891469-99-9
Target:
Research Areas:
JAK-IN-30 (compound 31) is a water-soluble JAK inhibitor with IC50 values of 2, 15, 18 and 2 nM for JAK2, JAK1, JAK3 and TYK2, respectively. JAK-IN-30 has research potential for dry eye disease (DED) .
Cat. No.: HY-RS27199
Target:
Research Areas:
Aatf Rat Pre-designed siRNA Set A contains three designed siRNAs for Aatf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-182307
CAS No.: 1018153-87-1
Target:
Research Areas:
OH14 is a cellular FLICE-like inhibitory protein (cFLIP) inhibitor and TNF-related apoptosis-inducing ligand (TRAIL) sensitizer. OH14 selectively binds to the DED1 pocket of cFLIP, disrupting its recruitment to the TRAIL-death inducing signalling complex without affecting procaspase-8 recruitment to FADD, allowing procaspase-8 activation. OH14 promotes TRAIL-mediated apoptosis and impairs cell viability in breast cancer systems when combined with TRAIL. OH14 can be used for the research of breast cancer .
Cat. No.: HY-P810457
Synonyms: TNFAIP8, TNF Alpha Induced Protein 8, MDC-3.13, SCC-S2, GG2-1, Head And Neck Tumor And Metastasis-Related Protein, Tumor Necrosis Factor Alpha-Induced Protein 8, NF-Kappa-B-Inducible DED-Containing Protein, TNF-Induced Protein GG2-1, NDED
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
