8 Results for "

Digitoxin

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Digitoxin" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-B1357
CAS No.: 71-63-6
Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .
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1
1 Cited Publications
Cat. No.: HY-16022
CAS No.: 1111-39-3
Synonyms: Digitoxin 3'''-Acetate
Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch .
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Cat. No.: HY-136933
CAS No.: 4562-36-1
Gitoxin is a degradation metabolite of Digitoxin (HY-B1357) and a non-competitive Na +/K +-ATPase inhibitor, with an IC50 of 1.18e-6 M against the porcine high-affinity subtype and an IC50 of 2.85e-5 M against the porcine low-affinity subtype. Gitoxin regulates atrial contractility and rhythmicity. Gitoxin is applicable to research related to congestive heart failure .
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Cat. No.: HY-B1357R
CAS No.: 71-63-6
Digitoxin (Standard) is the analytical standard of Digitoxin. This product is intended for research and analytical applications. Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .
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Cat. No.: HY-W747795
CAS No.: 26970-68-3
Digitoxin-d3 is the deuterium labeled Digitoxin-d3 (HY-W747795) .
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Cat. No.: HY-106831
CAS No.: 104606-13-5
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

R 56865 is a cardiomyocyte protective agent that protects against digitoxin (Ouabain)-induced myocardial calcium overload. R 56865 has a protective effect against digitoxin-induced intoxication in guinea pig papillary muscle .
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Cat. No.: HY-164033
CAS No.: 33156-28-4
Synonyms: Ramnodigin
Target:  

Apoptosis

Research Areas:  

Cancer

HOE 689 (Ramnodigin) is an analog of Digitoxin (HY-B1357). HOE 689 exhibits cytotoxicity to lung cancer cells and induces apoptosis in cancer cell NCI-H460 with an IC50 of 52 nM .
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Cat. No.: HY-136933R
CAS No.: 4562-36-1
Gitoxin (Standard) is the analytical standard of Gitoxin. This product is intended for research and analytical applications. Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably .
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