Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
EES
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "EES" in MCE Product Catalog:
1
1 Cited Publications
Art. -Nr.: HY-120954
CAS. Nr.: 519038-92-7
Target:
Forschungsgebiete:
14,15-EE-5(Z)-E is a structural analogue of 14, 15-epoxide dicartrienoic acid (14,15-EET). 14,15-EE-5(Z)-E antagonizes the relaxation of vascular smooth muscle induced by EET .
1
1 Cited Publications
Target:
Forschungsgebiete:
YH239-EE, ethyl ester of the free carboxylic acid compound YH239, is a potent p53-MDM2 antagonizing and apoptosis-inducing agent.
Category:
Infection Microorganisms Antibiotics Antiviral Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
Art. -Nr.: HY-P11117
CAS. Nr.: 2899218-49-4
Target:
Forschungsgebiete:
Forschungsgebiete:
Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders. Mestranol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Category:
Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite
Target:
Art. -Nr.: HY-W701835
CAS. Nr.: 69977-24-8
Category:
Target:
(E/Z)-E64FC26 is a mixture of the stereoisomers E-E64FC26 and Z-E64FC26, in which E-E64FC26 is the active component and acts as a potent PDI inhibitor. The IC50 values of E64FC26 (E-E64FC26) for PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6 are 0.6, 4.8, 33.1, 12.1, and 5.7 μM, respectively. By inhibiting PDI, (E/Z)-E64FC26 causes massive intracellular accumulation of misfolded polyubiquitinated proteins, thereby triggering strong endoplasmic reticulum stress and oxidative stress responses, which in turn induce apoptosis. (E/Z)-E64FC26 is used in research on multiple myeloma, ovarian cancer, and breast cancer .
Art. -Nr.: HY-34740S
CAS. Nr.: 70907-93-6
Synonyms: X842
Target:
Forschungsgebiete:
Linaprazan glurate (X842) is an orally atcive prodrug of Linaprazan (HY-100412) with a potent and prolonged inhibitory effect on gastric acid secretion. Linaprazan glurate is rapidly transformed by enzymatic cleavage into its active metabolite, linaprazan. Linaprazan glurate is a potassium-competitive acid blocker. Linaprazan glurate selectively inhibites acid formation from gastric H⁺/K⁺-ATPase in a potassium-dependent manner (IC50 = 436.2 nM). Linaprazan glurate can be used for the studies of erosive esophagitis (EE) .
Art. -Nr.: HY-D2324
CAS. Nr.: 2804069-30-3
Art. -Nr.: HY-23206
CAS. Nr.: 1049720-51-5
Target:
Forschungsgebiete:
DAN-1 EE hydrochloride is a fluorescent indicator, which can be used for the detection of nitrite content in vitro and biological process .
Art. -Nr.: HY-W585959
CAS. Nr.: 62235-06-7
Target:
Art. -Nr.: HY-W068035
CAS. Nr.: 142-83-6
Synonyms: trans,trans-2,4-Hexadienal
Art. -Nr.: HY-B0957S
Synonyms: Erythromycin ethyl succinate-13C,d3; EES-13C,d3
Art. -Nr.: HY-177798
CAS. Nr.: 307535-32-6
Target:
Forschungsgebiete:
AChE-IN-98 (Compound 26) is an AChE inhitibor, with an IC50 value of 7.3 μM for ee AChE. AChE-IN-98 is also a Coumarin (HY-N0709) derivative. AChE-IN-98 can be used in the research of Alzheimer's disease .
Art. -Nr.: HY-165067
CAS. Nr.: 519038-93-8
Synonyms: 14,15-Epoxyeicosa-8(Z)-enoic acid
Target:
Forschungsgebiete:
14,15-EE-8(Z)-E (14,15-Epoxyeicosa-8(Z)-enoic acid) has potent vasodilator agonist activity in bovine coronary arteries. 14,15-EE-8(Z)-E is a 14,15-EET (HY-113489) analog. EETs represent important mediators of coronary vascular tone .
Synonyms: Erythromycin ethyl succinate (Standard); EES (Standard)
Art. -Nr.: HY-W742595
CAS. Nr.: 765-19-5
Category:
Target:
Art. -Nr.: HY-N12922
CAS. Nr.: 53880-51-6
Category:
Target:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
