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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
EF2
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "EF2" in MCE Product Catalog:
Cat. No.: HY-175164
SVC112 is a translation elongation inhibitor that prevents the cyclic dissociation of EF2 from the ribosome, thereby inhibiting the elongation step of translation. SVC112 shows activity in growth inhibition among cancer cell lines of various origins (acute myeloid leukemia (AML), multiple myeloma (Myeloma), colorectal cancer (CRC), and head and neck squamous cell carcinoma (HNSCC)). SVC112 preferentially impedes ribosomal processing of mRNAs, and decreaseds CSC-related proteins including Myc and Sox2. SVC112 induces apoptosis in hematologic cancer cell lines, while phosphorylation of c-Myc correlates with sensitivity to SVC112 in colorectal cancer cell lines. SVC112 inactivates HNSCC stem cells in vitro and prevents the regrowth of HNSCC tumor xenografts in mice. SVC112 can be used for the study of HNSCC [2].
Cat. No.: HY-128478
CAS No.: 11076-17-8
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Androgen receptor antagonist 12 (Compound EF2) is an orally active Androgen receptor (AR) antagonist (IC50: 0.30 μM). Androgen receptor antagonist 12 inhibits transcriptional activity of variant AR mutants and and the proliferation of AR-positive PCa cell lines. Androgen receptor antagonist 12 blocks AR nuclear translocation. Androgen receptor antagonist 12 inhibits tumor growth in a C4-2B xenograft mouse model. Androgen receptor antagonist 12 can be used for prostate cancer (PCa) research .
Cat. No.: HY-P704289
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Elongation factor 2; EEF2; EF2; EF-2
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Cat. No.: HY-P82836A
Synonyms: EEF2; EF2; Elongation factor 2; EF-2
Cat. No.: HY-E71402
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2-(3-Amino-3-carboxypropyl)histidine synthase (EC 2.5.1.108) is a [4Fe-4S] enzyme that modifies a histidine residue of translation elongation factor 2 (EF2) via a 3-amino-3-carboxypropyl radical. 2-(3-Amino-3-carboxypropyl)histidine synthase (EC 2.5.1.108) is involved in the biosynthesis of diphthamide.
Cat. No.: HY-RS04180
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EEF2 Human Pre-designed siRNA Set A contains three designed siRNAs for EEF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19149
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Npr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20725
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Eef2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eef2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27237
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Eef2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eef2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
