FN1

By Targets:	Discoidin Domain Receptor (1) Galectin (1) Phosphatase (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (1) Inflammation/Immunology (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-138657

NCGC00378430 2 Publications Verification	Phosphatase	Cancer
NCGC00378430 is a potent *SIX1/EYA2* interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model ^[1].

HY-RS23207

Fn1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fn1 Rat Pre-designed siRNA Set A Fn1 Rat Pre-designed siRNA Set A

HY-RS05013

FN1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
FN1 Human Pre-designed siRNA Set A contains three designed siRNAs for FN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

FN1 Human Pre-designed siRNA Set A FN1 Human Pre-designed siRNA Set A

HY-RS16767

Fn1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Fn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Fn1 Mouse Pre-designed siRNA Set A Fn1 Mouse Pre-designed siRNA Set A

HY-179410

Galectin-3-IN-7	Galectin	Others
Galectin-3-IN-7 is a selective Galectin-3 inhibitor with a K_d of 5.7 nM and shows 390-fold selectivity over Gal-1. Galectin-3-IN-7 can downregulate profibrotic signaling such as ACTA2, COL1A2, and FN1 in TGFβ-stimulated LX2 hepatic stellate cells. Galectin-3-IN-7 can be used for the research of fibrosis ^[1].

HY-P992066

Anti-Mouse DDR2 Antibody (DAB0065)	Discoidin Domain Receptor	Inflammation/Immunology
Anti-Mouse DDR2 Antibody (DAB0065) is a mAb that specifically targets mouse discoidin domain receptor DDR2 without cross-reacting with *DDR1. Anti-Mouse DDR2 Antibody (DAB0065) binds to the extracellular domain of native mouse DDR2, induces endocytosis and lysosomal degradation of DDR2, and this process is independent of collagen binding. Anti-Mouse DDR2 Antibody (DAB0065) exhibits significant therapeutic effects in both the unilateral ureteral obstruction (UUO) mouse model of renal fibrosis and the bleomycin (HY-108345)-induced mouse model of pulmonary fibrosis, effectively downregulating the mRNA expression of type I collagen Col1a1 and fibronectin Fn1*. Anti-Mouse DDR2 Antibody (DAB0065) can be humanized and has the potential to be developed as a targeted agent for diseases such as idiopathic pulmonary fibrosis and renal fibrosis ^[1] .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990927

Micvotabart PYX-201 Antibody	Inhibitory Antibodies	Inflammation/Immunology
HY-P990927 is an *FN1*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) ^[1].

HY-P992066

Anti-Mouse DDR2 Antibody (DAB0065)	Discoidin Domain Receptor	Inflammation/Immunology
Anti-Mouse DDR2 Antibody (DAB0065) is a mAb that specifically targets mouse discoidin domain receptor DDR2 without cross-reacting with *DDR1. Anti-Mouse DDR2 Antibody (DAB0065) binds to the extracellular domain of native mouse DDR2, induces endocytosis and lysosomal degradation of DDR2, and this process is independent of collagen binding. Anti-Mouse DDR2 Antibody (DAB0065) exhibits significant therapeutic effects in both the unilateral ureteral obstruction (UUO) mouse model of renal fibrosis and the bleomycin (HY-108345)-induced mouse model of pulmonary fibrosis, effectively downregulating the mRNA expression of type I collagen Col1a1 and fibronectin Fn1*. Anti-Mouse DDR2 Antibody (DAB0065) can be humanized and has the potential to be developed as a targeted agent for diseases such as idiopathic pulmonary fibrosis and renal fibrosis ^[1] .

Species:	Human (7)
Tag:	His (5) Tag Free (1) Avi (1) Fc (1)
Source:	HEK293 (5) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72370

	Fibronectin Protein, Human (Biotinylated, His-Avi) Fibronectin; FN1	Human	E. coli
	Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin Protein, Human (Biotinylated, His-Avi) is the recombinant human-derived Fibronectin protein, expressed by E. coli , with N-Avi, N-6*His labeled tag.

HY-P700991

	Fibronectin Protein, Human (314a.a, HEK293, His) FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF	Human	HEK293
	Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin Protein, Human (314a.a, HEK293, His) is the recombinant human-derived Fibronectin protein, expressed by HEK293 , with C-His labeled tag.

HY-P700992

	Fibronectin Protein, Human (571a.a, HEK293, His) FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF	Human	HEK293
	Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin Protein, Human (571a.a, HEK293, His) is the recombinant human-derived Fibronectin protein, expressed by HEK293 , with C-His labeled tag.

HY-P73063

	Fibronectin Protein, Human (HEK293, His) 1 Publications Verification Fibronectin; FN; Cold-insoluble globulin; CIG; FN1	Human	HEK293
	Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin Protein, Human (HEK293, His) is the recombinant human-derived Fibronectin protein, expressed by HEK293 , with C-His labeled tag.

HY-P703742

	Fibronectin Protein, Human (91a.a, HEK293, hFc) Fibronectin; FN1; Cold-insoluble globulin (CIG); FN	Human	HEK293
	Fibronectin (1266-1356) Protein, Human (HEK293, hFc) is the recombinant human-derived Fibronectin protein, expressed by HEK293, with C-hFc tag.

HY-P703663

	Fibronectin Protein, Human (91a.a, HEK293, His) FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF	Human	HEK293
	Fibronectin Protein, Human (91a.a, HEK293, His) is the recombinant human-derived Fibronectin protein, expressed by HEK293, with C-His tag.

HY-P703668

	*Fibronectin/FN1* Protein, Human** CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF	Human	E. coli
	Fibronectin binds collagen, fibrin, heparin, DNA, and actin. It is involved in cell adhesion, motility, opsonization, wound healing and maintenance of cell shape. Fibronectin/FN1 Protein, Human is the recombinant human-derived Fibronectin/FN1 protein, expressed by E. coli, with tag free.

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Host:	Mouse (1) Rabbit (2)
Reactivity:	Human (3) Rat (2) Mouse (3)
Application:	IHC-P (3) ICC/IF (3) IF-Tissue (1) IHC-F (1) WB (3) ELISA (1)
Isotype:	IgG (1) IgG1 (1) IgG,IgG/Kappa (1)
Conjugation:	Non-conjugated (3) Biotin (1)
Clonality:	Monoclonal (3) Recombinant (1)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86415

	Fibronectin Antibody (YA6107) FN1; FN; Fibronectin; FN; Cold-insoluble globulin; CIG	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Fibronectin Antibody (YA6107) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fibronectin.

HY-P80674

	Fibronectin Antibody (YA762) 1 Publications Verification FN1; FN; Fibronectin; FN; Cold-insoluble globulin; CIG	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Fibronectin Antibody (YA762) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fibronectin.

HY-P80493

	Fibronectin Antibody (YA436) 1 Publications Verification	WB, IHC-P, ICC/IF, IF-Tissue	Human, Mouse
	Fibronectin Antibody (YA436) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fibronectin.

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Products	In-stock - + Add to Cart
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Host
Reactivity
Application
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Molecular Weight
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Clonality
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS23207

Fn1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Fn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS05013

FN1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
FN1 Human Pre-designed siRNA Set A contains three designed siRNAs for FN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16767

Fn1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Fn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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