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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
FN1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "FN1" in MCE Product Catalog:
2
2 Cited Publications
Target:
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NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-β signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model [1].
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Cat. No.: HY-RS23207
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Fn1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05013
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FN1 Human Pre-designed siRNA Set A contains three designed siRNAs for FN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P5237
CAS No.: 960608-16-6
Cat. No.: HY-RS16767
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Fn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990927
CAS No.: 2867549-73-1
Synonyms: PYX-201 Antibody
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Cat. No.: HY-179410
Galectin-3-IN-7 is a selective Galectin-3 inhibitor with a Kd of 5.7 nM and shows 390-fold selectivity over Gal-1. Galectin-3-IN-7 can downregulate profibrotic signaling such as ACTA2, COL1A2, and FN1 in TGFβ-stimulated LX2 hepatic stellate cells. Galectin-3-IN-7 can be used for the research of fibrosis [1].
Cat. No.: HY-P700991
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Cat. No.: HY-P700992
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Cat. No.: HY-P706119
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Cat. No.: HY-P703742
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Fibronectin; FN1; Cold-insoluble globulin (CIG); FN
Cat. No.: HY-P703663
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN; CIG; FN1; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Cat. No.: HY-P992066
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Cat. No.: HY-P703668
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF
Cat. No.: HY-184654
CAS No.: 2169267-60-9
Target:
Synaptic Vesicle Proteins NF-κB ERK Akt HIF/HIF Prolyl-Hydroxylase Interleukin Related MyD88 TNF Receptor Caspase Formyl Peptide Receptor (FPR)
Research Areas:
MR-39 is a FPR2 agonist (EC50 = 3.9 μM). MR-39 activates FPR2 to promote neuroinflammation resolution (downregulates IL-1β and TNF-α, modulates NF-κB), upregulates synaptic proteins (synaptic proteins) and improves dendritic spine morphology. MR-39 inhibits MAPK/ERK and AKT phosphorylation in glioblastoma, induces S-phase arrest, and suppresses migration, angiogenesis, and hypoxic adaptation. MR-39 reduces Aβ plaque burden via inhibiting MyD88/NF-κB and NLRP3 inflammasome. MR-39 can be used for research on autism spectrum disorder, Alzheimer's disease, and glioblastoma [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
